Title Application of toxicogenomics to cross-species extrapolation : report of a workshop / Committee on Applications of Toxicogenomics to Cross-Species Extrapolation, Committee on Emerging Issues and Data on Environmental Contaminants, Board on Environmental Studies and Toxicology, Board of Life Sciences, Division on Earth and LIfe Studies, National Research Council of the National Academies

Published Washington, D.C. : National Academies Press, ©2006

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Description 1 online resource (xii, 43 pages) : illustrations, charts Series Online access: NCBI NCBI Bookshelf Contents Emerging molecular and computational approaches for cross-species extrapolation -- Potential implications of genomics for risk assessment -- Technological challenges of cross-species extrapolation using proteomics -- Modeling gene-expression data to predict human hepatotoxicity after inconsistent animal responses -- Using metabolomics to explore species differences in metabolism and distribution -- A systems-biology approach to cross-species extrapolation -- Combining transcriptional and toxicologic approaches to understanding the basis of species differences in conazole carcinogenesis -- Species differences in response to perfluorooctanoic acid Summary Considers strategies for communicating toxicogenomic information to the public and other non-expert audiences, specifically addressing the communication of some key social, ethical, and legal issues related to toxicogenomics and addressing how information related to the social implications of toxicogenomics might be perceived by nonexperts Bibliography Includes bibliographical references Notes English Print version record Subject Toxicology. Environmental sciences. Toxicogenetics Toxicology toxicology. environmental sciences. HEALTH & FITNESS -- Diseases -- Genetic. MEDICAL -- Genetics. Environmental sciences Toxicology Form Electronic book Author National Research Council (U.S.). Committee on Applications of Toxicogenomics to Cross-Species Extrapolation. ISBN 0309656133 9780309656139 128044746X 9781280447464 9786610447466 6610447462

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