Preface; Chapter 1; Optimization of Adhesion Molecule Evaluation on In Vitro-Amplified Bone Marrow-Derived Mesenchymal Stromal Cells from Healthy Donors; Abstract; Abbreviations; Introduction; Materials and Methods; Experimental Design; Isolation and Expansion of Human MSCs from Bone Marrow (BM) Aspirates; EasySep Immunomagnetic Selection of STRO-1+ and STRO-1-/CD73+ hBM-MSCs; Cell Yield and Growth Kinetics of hBM-MSCs in a Culture System; Flow Cytometric Analysis of hBM-MSC Adhesion Molecule Expression; Statistical Analysis; Results
Uses of ASC for Inhibiting Tumor ProliferationThe Effect of ASC on Promoting Tumor Cell Proliferation; Angiogenesis Can Be Influenced by ASC-Mediated Signaling; Uses of ASC for Treating Tumor Angiogenesis; The Effects of ASC in Promoting Tumor Angiogenesis; ASC May Modulate Metastatic Ability of Dormant Tumor Cells; Uses of ASC for Preventing Tumor Cell Metastasis; The Effects of ASC in Promoting Tumor Cell Metastasis; ASC May Influence the Immune Response within the Tumor Microenvironment; Uses of ASC for Promoting an Immune-Mediated Anti-Tumor Response
The Effects of ASC in Promoting Tumorigenesis via Effects on the Immune SystemChallenges of ASC-Based Therapies: Tilting the Scale between Tumor Promotion and Inhibition; Conclusion; References; Chapter 3; Improving Clinical Uses of Mesenchymal Stromal Cells by 3D Scaffold-Free Constructs; Abstract; 1. Mesenchymal Stromal Cells; 1.1. MSCs Cell Suspension in Cell Therapy; Conclusion; 2. Top-Down Tissue Engineering; 2.1. Understanding Scaffolds in Cell and Tissue Microenvironment; Conclusion; 3. Scaffold-Free 3D Constructs in; Tissue Engineering
3.1. Technologies for Scaffold-Free 3D Construct Biofabrication3.2. MSCs Scaffold-Free 3D Constructs; Conclusion; 4. MSCs as Scaffold-Free 3D Constructs for Cell Delivery Improvement; 4.1. MSCs Spheroids in Bone Regeneration; 4.2. MSCs Spheroids in Cartilage Regeneration; 4.3. MSCs Spheroids for Ischemic Injuries Treatment; 4.4. MSCs Aggregates and Spheroids for Cardiac; Therapeutic Approaches; 4.5. MSCs Aggregates and Spheroids in Diabetic Wound Healing; Conclusion; 5. Bottom-Up Tissue Engineering; 5.1. What are Building-Blocks?; 5.1.1. Cell Sheets; 5.1.2. Cell-Laden Hydrogels
Bibliography
Includes bibliographical references and index
Notes
Description based on print version record and CIP data provided by publisher
