| Description |
1 online resource (198 pages) |
| Contents |
Intro; Foreword; Preface; Acknowledgements; Abbreviations; Contents; Editors and Contributors; Part I: Medieval Perspective; 1: Medieval English Social Inequality and Bone Health: What Lessons are There to be Learnt for the Living?; 1.1 Introduction; 1.2 The Medieval Social Mosaic and Human Skeletal Remains; 1.3 Medieval Social Status Occupations, Bone Health, and Modern Epidemiological Parallels; 1.4 Conclusion; References; 2: Skeletal Health in Medieval Societies: Insights from Ancient Bone Collagen Stable Isotopes and Dental Histology; 2.1 Introduction; 2.2 Medieval Human Bone |
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2.3 High-Protein Diet and High SES in Medieval English Human Bone: Insights from Bone Collagen Stable Isotopes2.3.1 Brief Background; 2.3.2 Materials and Methods; 2.3.3 Results; 2.3.4 Discussion and Conclusions; 2.4 Stress, Weaning, and SES in Medieval Canterbury: Insights from Dental Histology; 2.4.1 Brief Background; 2.4.2 Materials and Methods; 2.4.3 Results; 2.4.4 Discussion and Conclusions; 2.5 Conclusions; References; 3: Ancient Human Bone Microstructure Case Studies from Medieval England; 3.1 Introduction |
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3.2 Medieval Individuals from High SES Backgrounds Achieve Higher Bone Density Despite Experiences of Childhood Developmental Disruption3.2.1 Brief Background; 3.2.2 Sample and Methods; 3.2.3 Results; 3.2.4 Discussion and Conclusions; 3.3 Histomorphometry of Cortical Bone in the Human Radius; 3.3.1 Brief Background; 3.3.2 Sample and Methods; 3.3.2.1 Image Analysis; 3.3.2.2 Statistical Analysis; 3.3.3 Results; 3.3.3.1 Linear Regressions; 3.3.3.2 Correlations; 3.3.4 Discussion and Conclusions; 3.4 Conclusion; References; Part II: Contemporary Perspective |
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4: Bone Quality in Socially and Ethnically Diverse Groups: Downstream and Upstream Determinants Across the Life Course4.1 Social Determinants of Health; 4.2 Education and Income; 4.3 Ethnicity; 4.4 Life Course Trajectory of Bone Accrual and Loss; 4.5 Health Literacy: An Influence Across the Life Course; 4.6 Conclusion; References; 5: Differences in Fracture Risk Between Countries, Within Countries and Between Social and Ethnic Groups; 5.1 Introduction; 5.2 Between-Country Differences in Fracture; 5.3 Within-Country, Between-Ethnicity Differences in Fracture |
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5.4 Vitamin D [Sun Exposure]: Key Risk Factor for Fracture5.5 Diabetes: Key Risk Factor for Fracture; 5.6 Disparities in Fracture Risk Across Social Groups; 5.7 Conclusion; References; 6: Social Determinants of Preventive Testing and Adherence to Treatment for Osteoporosis; 6.1 Introduction; 6.2 Preventive Testing; 6.3 Non-pharmacological Treatment; 6.4 Worldwide 'Care Gap' in Osteoporosis and Fracture Treatment; 6.5 Postfracture Care Pathways; 6.6 Adherence to Osteoporosis Treatment and Management; 6.6.1 Patients; 6.6.2 Healthcare Providers; 6.7 Health Policy; 6.8 Conclusion |
| Summary |
This multidisciplinary book addresses three lines of evidence (medieval, contemporary, and epigenetic) regarding the effect of human socio-economic status on bone health. It provides an overview of the extent to which human social background affects adult bone quality and quantity, and makes recommendations for future skeletal biology research into lifestyle-related musculoskeletal disorders. The book is divided into three major parts, the first of which discusses bone and dental health in medieval human skeletal remains from distinct socio-economic status groups. In turn, Part 2 reviews bone health in contemporary human populations with a range of social backgrounds; in addition, a conceptual model proposing a social gradient of osteoporosis and fracture risk related to biological mechanisms and cumulative stressors throughout the human lifecycle is presented. Lastly, Part 3 highlights the role of epigenetics in socially patterned risk factors for skeletal disorders, and discusses how epigenetic mechanisms transduce the psychosocial environment and increase the risk of developing conditions such as osteoporosis. Overall, the book highlights the importance of considering the social-biological nexus in future skeletal biology research and future treatment of bone disease. Increased awareness of this nexus can potentially improve individual and population-level bone health interventions, reducing the social inequities observed in fracture risk. Given its scope, the book offers a valuable resource for researchers, academics, and students in the fields of medicine, epidemiology, the health sciences, biological anthropology, human anatomy and adaptation, developmental studies of human societies, human biology, and any field concerning musculoskeletal disorders and health. It will also benefit clinical practitioners evaluating osteoporosis, osteopenia, fracture risk, bone quality and quantity |
| Bibliography |
References |
| Notes |
Print version record |
| Subject |
Bones.
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Bones -- Diseases.
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Baby bonnets.
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Bone and Bones
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Bone Diseases
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bonnets (hats)
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bone (material)
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Bones
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Bones -- Diseases
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| Form |
Electronic book
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| Author |
Miszkiewicz, Justyna J
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Brennan-Olsen, Sharon L
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Riancho, José A
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| ISBN |
9789811372568 |
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981137256X |
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