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Book Cover
E-book
Author Arbuthnot, Patrick

Title Molecular Medicine for Clinicians
Published Johannesburg : Witwatersrand University Press, 2008

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Description 1 online resource (531 pages)
Contents Front Cover; Title Page; Copyright; Table of Contents; Foreword; Acknowledgements; Chapter 1 Introduction; Keynote Essay 1: Defining Who We Are: DNA in Forensics, Genealogy and Human Origins; Section 1 Principles of Cellular and Molecular Biology; Chapter 2 Digital Concepts in Molecular Medicine; Chapter 3 The Anatomy and Physiology of the Genome; Chapter 4 Molecular Cell Biology; Chapter 5 Genetic Variation; Chapter 6 Genes in Development; Chapter 7 Tools of Molecular Medicine; (a) Nucleic Acid Methods; (b) Protein Methods; (c) Cellular Phenotyping and Flow Cytometry
(D) Molecular CytogeneticsKeynote Essay 2: The Human Genome; Section 2 Molecular Pathology; Chapter 8 Genomes and the Environment: An Overview of Molecular Pathology; Chapter 9 Genetics, Genomics, Health and Disease: General Considerations; Chapter 10 Chromosome Disorders; Chapter 11 Mendelian Inheritance; Chapter 12 Unusual Molecular Processes that Impact on Disease; Chapter 13 Population Genetics; Chapter 14 Complex Multifactorial Inheritance; Chapter 15 Molecular Basis for Phenotypic Variation; Chapter 16 Medical Genetics; Keynote Essay 3: Human Cloning: Should We Go There?
Chapter 17 Neoplasia: General ConsiderationsChapter 18 Oncogenes; Chapter 19 Mammalian DNA Repair; Chapter 20 Tumour Suppressor Genes and Inherited Susceptibility to Cancer; Chapter 21 Carcinoma; Chapter 22 Leukaemias and Lymphomas; Chapter 23 Molecular Approaches to the Diagnosis, Prognostication and Monitoring of Cancer; Keynote Essay 4: Microbes, Molecules, Maladies and Man; Chapter 24 Molecular Basis of Infectious Diseases: General Considerations; Chapter 25 Immunology; Chapter 26 Human Immunodeficiency Virus; Chapter 27 Tuberculosis; Chapter 28 Malaria; Chapter 29 Influenza
Chapter 30 Oncogenic VirusesChapter 31 Vaccines and Immunisation; Keynote Essay 5: Drugs and the 21st Century; Section 3 Molecular Therapeutics; Chapter 32 Targets for Molecular Therapy: The Biology of Haemostasis; Chapter 33 Cellular Targets of Antiplatelet Agents; Chapter 34 Rational Drug Design; Chapter 35 Chronic Myeloid Leukaemia; Chapter 36 Gene Therapy; Chapter 37 Diabetes Mellitus; Chapter 38 Pharmacogenetics; Chapter 39 Basic Molecular Biology of Blood Groups; Keynote Essay 6: Molecular Research Case Study: Developing Novel RNA Interference-based Therapy
Section 4 Research and the Continuing Evolution of Molecular MedicineChapter 40 Approaches to Research in Molecular Medicine; Chapter 41 Bioinformatics and Molecular Medicine; Chapter 42 Personalised Medicine: Dream or Reality?; Glossary; Contributors' Biographies; Source Material and Recommended Reading; Permissions and Credits; Index; Back Cover
Summary This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under- and postgraduate science and engineering students. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere
Notes Print version record
Subject Molecular biology -- Textbooks
Medical genetics -- Textbooks
Bioinformatics -- Textbooks
SCIENCE -- Life Sciences -- Molecular Biology.
Bioinformatics
Medical genetics
Molecular biology
Genre/Form Textbooks
Form Electronic book
Author Arndt, Silke
Asfaha, Sahle
Brown, Jacqueline
Capovilla, Alexio
Christianson, Arnold
Mendelow, Barry
Ramsay, Michèle
Chetty, Nanthakumarn
Stevens, Wendy
ISBN 9781868147137
1868147134