| Description |
1 online resource (xix, 454 pages) : illustrations (some color) |
| Series |
Cancer growth and progression ; v. 15 |
|
Cancer growth and progression ; v. 15.
|
| Contents |
Microenvironmental effects on tumour progression and metastasis -- Role of microenvironment on gene expression, angiogenesis and microvascular function in tumors -- Imaging of angiogenesis in vivo with fluorescent proteins -- The epigenetic influence of the tumor microenvironment on melanoma plasticity -- Dynamics of cell adhesion interactions during melanoma development -- Matrix metalloproteinases: mediators of tumour-host cell interactions -- Role of brain microenvironments in brain metastases -- Influence of the bone microenvironment on breast cancer metastasis to bone -- Interaction of tumour with host stroma in hepatocellular carcinoma -- Dynamic nature of tumour-host interactions within the tumor microenvironment -- Breast cancer progression: a "vicious cycle" of pro-malignancy activities is mediated by inflammatory cells, chemokines and cytokines -- Tumor and host endothelial cell selective interactions and modulation by microenvironmental chemokines: tumor-endothelial cell cross talk specificity -- The role of chemokine receptors, in particular CXCR4, in lymphoma and carcinoma metastasis -- Energy homeostasis and the tumor/host interaction: the role of the brain -- Anti-angiogenic and pro-apoptotic effects of dietary restriction in experimental brain cancer: role of glucose and ketone bodies -- Dietary restriction of specific amino acids modulates tumor and host interactions -- Role of tumour microenvironment in chemoresistance -- Integrin-mediated resistance to chemotherapy-induced apoptosis in cancer cells -- Bone metastasis microenvironment participates in the development of androgen ablation refractoriness and chemotherapy resistance of prostate cancer cells residing in the skeleton: clinical implications -- Current and future therapeutic targets of the tumour-host microenvironment -- Bone stromal cells as therapeutic targets in osseous metastasis -- Organtropism of lung cancer metastasis and its molecular targeted therapy -- Maspin: a novel serine protease inhibitor -- Metastasis suppressor genes: a brief review of an expanding field -- Tumor-host interactions at the metastatic site: MKK4, signal transduction and the stress response |
| Summary |
"This book addresses the interactions and interrelationships between tumor and host that modulate progression and metastasis. A unique aspect of the book is that it highlights the tumor/host interactions as new targets for therapeutic intervention to control cancer. One promising approach is to target the host rather than the tumor itself, and several authors examine the potential for this novel tactic to oppress the manipulative cancer cell. The book examines the tumor and host relationship from multiple viewpoints: cellular and molecular events that occur during tumor-host cell interactions that control differentiation, cell proliferation, angiogenesis and vasculogenic mimicry, migration, apoptosis, invasion, metastasis."--Jacket |
| Analysis |
neoplasms |
|
immunologie |
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immunology |
|
geneeskunde |
|
medicine |
|
biomedische wetenschappen |
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biomedicine |
|
levenswetenschappen |
|
life sciences |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer e-books |
| Subject |
Metastasis.
|
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Cancer -- Treatment.
|
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Life sciences.
|
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Neoplasm Metastasis -- physiopathology
|
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Neoplasm Metastasis
|
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Neoplasms -- therapy
|
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Tumor Microenvironment
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Biological Science Disciplines
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medicines (material)
|
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biological sciences.
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MEDICAL -- Oncology.
|
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HEALTH & FITNESS -- Diseases -- Cancer.
|
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Cancer -- Treatment.
|
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Neoplasm Metastasis -- physiopathology.
|
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Neoplasms -- therapy.
|
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Metastasis.
|
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Biomédecine.
|
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Sciences de la vie.
|
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Cancer -- Treatment
|
|
Metastasis
|
| Form |
Electronic book
|
| Author |
Meadows, Gary G. (Gary Glenn), 1945-
|
| LC no. |
2005283165 |
| ISBN |
9781402034145 |
|
1402034148 |
|
140203413X |
|
9781402034138 |
|
1280283785 |
|
9781280283789 |
|
6610283788 |
|
9786610283781 |
|
