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Title ADQI consensus on AKI biomarkers and cardiorenal syndromes / volume editors, Peter McCullough, John A. Kellum, Ravindra L. Mehta, Patrick Murray, Claudio Ronco
Published Basel : Karger, 2013

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Description 1 online resource
Series Contributions to nephrology, 0302-5144 ; vol. 182
Contributions to nephrology ; v. 182.
Contents Cover; Front matter; Contents; Preface; Acute Dialysis Quality Initiative (ADQI); Abstract; References; Implementation of Novel Biomarkers in the Diagnosis, Prognosis, and Management of Acute Kidney Injury: Executive Summary from the Tenth Consensus Conference of the Acute Dialysis Quality Initiative (ADQI); Abstract; Methods; Results; Differential Diagnosis; Prognosis and Management; Physiologic and Imaging Measures; Conclusions; Acknowledgements; References
Diagnosis of Acute Kidney Injury Using Functional and Injury Biomarkers: Workgroup Statements from the Tenth Acute Dialysis Quality Initiative Consensus ConferenceAbstract; Methods; Results; Risk Assessment; Diagnosis of AKI; Normal Levels and Thresholds for Detection for Diagnosis of AKI; Staging of AKI and the Role of Serial Measurement; Opportunities for Future Research; Conclusion; References; Differential Diagnosis of AKI in Clinical Practice by Functional and Damage Biomarkers: Workgroup Statements from the Tenth Acute Dialysis Quality Initiative Consensus Conference; Abstract; Methods
Transient AKI, Not Pre-RenalEtiology of AKI; Setting, Mechanism and Time Course of AKI; Differential Diagnosis in the Presence of CKD; Non-Renal Biomarkers and Etiology of AKI; Conclusion; References; Use of Biomarkers to Assess Prognosis and Guide Management of Patients with Acute Kidney Injury; Abstract; Methods; Results; Conclusion; References; Physiological Biomarkers of Acute Kidney Injury: A Conceptual Approach to Improving Outcomes; Abstract; Methods; Results; Renal Blood Flow, Tissue Oxygenation and Microcirculatory Function: Critical Physiological Biomarkers
Glomerular Filtration Rate, Continuous Urine Output Measurement, and Urine IndicesAssessment of Renal Tissue Perfusion; Assessment of Kidney Oxygenation and Metabolism; Application of Physiological Biomarkers for Assessment and Management of AKI; Conclusions; Acknowledgements; References; Pathophysiology of the Cardiorenal Syndromes: Executive Summary from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI); Abstract; Methods; Results; Conclusions; Acknowledgements; References
Pathogenesis of Cardiorenal Syndrome Type 1 in Acute Decompensated Heart Failure: Workgroup Statements from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)Abstract; Methods; Results; References; Pathophysiology of Cardiorenal Syndrome Type 2 in Stable Chronic Heart Failure: Workgroup Statements from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI); Abstract; CRS2 in Stable Chronic Heart Failure; Animal Models and Pathophysiological Insights into CRS2; Clinical Studies and Pathophysiological Insights into CRS2
Summary Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This book contains the resolutions of the most recent ADQI conferences on biomarkers in AKI (Dublin) and on cardio-renal syndromes (Venice). The first part answers specific questions about new biomarkers and their use and utility in AKI: What are the most suitable candidate molecules and physiologic measures, how solid and evidence based is the discovery phase? How can we incorporate the new biomarkers in the AKI conceptual model describing the evolution from susceptibility to insult, decreased GFR and organ death? Even if we have a positive biomarker pattern and we can identify patients at risk or patients with early or even subclinical AKI, how is this information affecting our clinical behavior and practice? The second part is dedicated to the appraisal of the current knowledge about the pathophysiological mechanisms involved in different forms of CRS: it contains contributions on the state-of-the-art knowledge and practice of CRS, particularly focusing on the pathophysiology of the five subtypes. Acute and chronic mechanisms of damage are explored in depth, with particular attention to the primacy of organ involvement and the subsequent pathways of organ crosstalk. Presenting the most recent research in the field of biomarkers, AKI and CRS, this publication is an important educational tool for advanced investigators and clinical experts, but also for students and fellows
Bibliography Includes bibliographical references and indexes
Subject Kidneys -- Diseases -- Surgery
Acute renal failure.
Biochemical markers.
Acute Kidney Injury
Biomarkers
Cardio-Renal Syndrome
MEDICAL -- Surgery -- General.
Acute renal failure.
Biochemical markers.
Cardiovascular system -- Diseases.
Hemodialysis.
Kidneys -- Diseases.
Biomarker
Herzinsuffizienz
Nierenversagen
Genre/Form Conference papers and proceedings.
Actes de congrès.
Form Electronic book
Author McCullough, Peter A., editor
Kellum, John A., editor
Mehta, Ravindra L., editor
Murray, Patrick T., editor
Ronco, C. (Claudio), 1951- editor.
Acute Dialysis Quality Initiative.
Conference on Biomarkers in AKI (10th : 2011 : Dublin, Ireland)
Conference on CRS (11th : 2012 : Venice, Italy)
ISBN 9783318024074
3318024074
Other Titles Acute Dialysis Quality Initiative consensus on acute kidney injury biomarkers and cardiorenal syndromes