Limit search to available items
Book Cover
E-book

Title Inflammation and epilepsy : new vistas / Damir Janigro, Astrid Nehlig, Nicola Marchi, editors
Published Cham : Springer, [2021]

Copies

Description 1 online resource (240 pages)
Series Progress in inflammation research ; volume 88
PIR (Series) ; volume 88.
Contents Pro and Anti-Inflammatory Neurovascular Processes in Epilepsy: A Fragile and Dynamic Equilibrium -- Emerging Molecular Mechanisms of Neuroinflammation in Seizure Disorders -- Glial Mechanisms of Inflammation during Seizures -- Perivascular Inflammation and Extracellular Matrix Alterations in Blood-Brain Barrier Dysfunction and Epilepsy -- Blood T cells and Cytokine Levels during Interictal-Ictal Transitions -- Autoantibodies, Encephalopathies and Epilepsy -- Tau Protein in Drug-Resistant Epilepsy and Cognitive Decline -- Ketogenic Diet, Inflammation and Epilepsy -- Role of Regulatory T cells in Epilepsy -- Inflammation at the Neurovascular Unit in Post-Traumatic Epilepsy
Summary This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways
Notes Print version record
Subject Epilepsy.
Epilepsy -- Treatment
Inflammation.
Epilepsy -- immunology
Epilepsy -- therapy
Inflammation
Epilepsy
Epilepsy -- Treatment
Inflammation
Form Electronic book
Author Janigro, Damir, editor.
Nehlig, Astrid, editor.
Marchi, Nicola, editor
ISBN 9783030674038
3030674037