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Book Cover
E-book
Author Laurent, Sophie, 1967- author.

Title MRI contrast agents : from molecules to particles / by Sophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid, Robert N. Muller, Luce Vander Elst
Published Singapore : Springer Singapore : Imprint : Springer, 2017
©2017

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Description 1 online resource (vii, 125 pages : 63 illustrations, 44 illustrations in color)
Series SpringerBriefs in Applied Sciences and Technology, 2191-530X
SpringerBriefs in applied sciences and technology, 2191-530X
Contents Nanomaterials in medicine -- Magnetic properties (diamagnetism, paramagnetism, ferromagnetism, ferrimagnetism, antiferromagnetism, superparamagnetism) -- Imaging probes -- Magnetic resonance imaging (MRI) -- Bases of MRI -- MRI contrast agents -- Paramagnetic gadolinium complexes -- Superparamagnetic iron oxide nanoparticles -- Synthesis of magnetic nanoparticles -- Stabilization of magnetic nanoparticles -- Physico-chemical characterization of nanoparticles -- MRI applications -- Conclusions
Summary This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc
Bibliography Includes bibliographical references
Subject Contrast-enhanced magnetic resonance imaging.
Magnetic resonance imaging.
Molecular biology.
Medical physics.
Radiation.
Nanotechnology.
Biomedical engineering.
Biomedical materials.
Radiographic contrast media.
Contrast media (Diagnostic imaging)
Contrast Media
Magnetic Resonance Imaging
Molecular Biology
Radiation
Biomedical Engineering
Biomedical Technology
Biocompatible Materials
Biomedical and Dental Materials
Nanotechnology
molecular biology.
biomedical engineering.
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Magnetic resonance imaging
Contrast-enhanced magnetic resonance imaging
Biomedical engineering
Biomedical materials
Engineering
Medical physics
Molecular biology
Nanotechnology
Radiation
Form Electronic book
Author Henoumont, Céline, author
Stanicki, Dimitri, author
Boutry, Sébastien, author
Lipani, Estelle, author
Belaid, Sarah, author
Muller, Robert N., author
Vander Elst, Luce, author
ISBN 9789811025297
9811025290
9789811025273
9811025274