| Description |
1 online resource |
| Series |
Springer series in translational stroke research |
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Springer series in translational stroke research.
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| Contents |
Part 1. Calcium (Ca) -- Mechanisms of Calcium Influx Following Stroke / Jillian C. Belrose, Fabiana A. Caetano, Kai Yang, Brian M.W. Lockhart and Michael F. Jackson, et al. -- Mitochondrial Ca2+ Dysregulation During Stroke and Cell Death / Maria Josè Sisalli, Claudia Savoia and Antonella Scorziello -- Calcium Channel Blockers and Stroke Prevention / Anna Poggesi and Domenico Inzitari -- Calcium Dyshomeostasis in Astrocytes After Ischemia / Elena Alberdi, María Domercq and Carlos Matute -- Calcium Signaling at the Blood-Brain Barrier in Stroke / Rachel C. Brown -- Metal Ions in Stroke Pathophysiology / Yang V. Li and John H. Zhang |
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Part 2. Zinc in Stroke Pathophysiology -- Zinc Overload in Stroke / Yang V. Li -- Intracellular Zinc Liberation: A Trigger for Oxidative Stress-Induced Toxicity to Neurons and Neuroglia / Yumin Zhang -- Zinc in Stroke: Time for a New Approach? / Richard B. Thompson -- Exploring the Zinc Metallome of Cultured Cortical Neurons Using Synchroton Radiation X-Ray Fluorescence Microscopy / Robert A. Colvin, Christian J. Stork, Yang V. Li and Barry Lai |
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Part 3. Iron (Fe) -- Iron Neurotoxicity in Ischemic and Hemorrhagic Stroke / Chih Ming Lin and Magdy Selim -- Implication of Oxidative Stress and "Labile Iron" in the Molecular Mechanisms of Ischemic Stroke / Dimitrios Galaris, Natalia Kitsati, Sygkliti-Henrietta Pelidou and Alexandra Barbouti -- The Role of Iron in Brain Following Subarachnoid Hemorrhage / Jin-Yul Lee, Richard F. Keep, Ya Hua, Aditya Pandey and Guohua Xi -- Iron-Chelating Therapy in Stroke / Mónica Millán, Natalia Pérez de la Ossa and Teresa Gasull |
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Part 4. Sodium (Na) -- The Role of Na+/Ca2+ Countertransport and Other Na+-Entry Routes in the Pathophysiology of Stroke / Mauro Cataldi, Pasquale Molinaro and Lucio Annunziato -- Sodium and Potassium MRI in Cerebral Ischemia / Victor E. Yushmanov, Alexander Kharlamov, Fernando E. Boada and Stephen C. Jones |
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Part 5. Potassium (K) -- The Impact of Extracellular Potassium Accumulation in Stroke / Wolfgang Walz -- Potassium and Mitochondria / Piotr Bednarczyk -- Role of a Changing Membrane Potential (Em) and Matching Blood Flow with Neuronal Activity / David R. Harder, Maia Terashvili and Debebe Gebremedhin -- The Role of Potassium in Stroke, Cardiovascular Disease, and Hypertension / Mark C. Houston |
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Part 6. Magnesium (Mg) -- The Role of Magnesium in the Pathophysiology and Treatment of Stroke and Other Neurological Injuries / Michael R. Hoane -- Magnesium in Acute Brain Injury / Renée J. Turner, Frances Corrigan and Robert Vink -- Magnesium and Neuroprotection in Stroke / Bruno P. Meloni, Kym Campbell and Neville W. Knuckey -- Magnesium in Ischemic Stroke and Subarachnoid Hemorrhage / Peter Yat-Ming Woo, George Kwok-Chu Wong, Matthew Tak-Vai Chan and Wai Sang Poon |
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Part 7. Selenium (Se) -- Selenium and Selenoproteins in Neuroprotection and Neuronal Cell Death / Nic E. Savaskan, Nirjhar Hore and Ilker Y. Eyupoglu -- Selenium as a Potential Treatment in Cardiac Arrest Induced Global Cerebral Ischemia / Johann Reisinger |
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Part 8. Manganese (Mn) -- The Neurochemical Alterations Associated with Manganese Toxicity / Steven C. Fordahl and Keith M. Erikson -- Manganese Speciation Related to Neurotoxicity in Humans / Bernhard Michalke -- The Role of Mitochondrial Oxidative Stress and ATP Depletion in the Pathology of Manganese Toxicity / Thomas E. Gunter, Claire E. Gavin and Karlene K. Gunter |
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Part 9. Copper (Cu) -- Copper and Alzheimer Disease: The Good, the Bad and the Ugly / Ya Hui Hung, Ashley I. Bush and Robert A. Cherny |
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Part 10. Exogenous Metal Ions: Aluminum (Al); Arsenic (As); Cadmium (Cd); Mercury (Hg); Nickel (Ni) / Conjecturable Role of Aluminum in Pathophysiology of Stroke / Prasunpriya Nayak -- Chronic Arsenic Poisoning and Increased Risk of Stroke / Chih-Hao Wang and Chien-Jen Chen -- Aspects of Cadmium Neurotoxicity / Haris Carageorgiou and Myrto Katramadou -- Cadmium Neurotoxicity and Its Role in Brain Disorders / Rodrigo Bainy Leal, Débora Kurrle Rieger, Tanara Vieira Peres, Mark William Lopes and Carlos Alberto S. Gonçalves -- The Role of Mercury and Cadmium in Cardiovascular Disease, Hypertension, and Stroke / Mark C. Houston -- Nickel Modulation of Voltage- and Ligand-Gated Ionic Channels in Neurons / Carla Marchetti and Paola Gavazzo |
| Summary |
Annotation Stroke is a major cause of death and disability in the U.S. and worldwide. A variety of pathophysiologic episodes or cellular medications occur following a stroke, and knowledge of these aftermath events can lead to potential therapeutic strategies that may reverse or attenuate stroke injury. Cellular events that occur following stroke include the excessive releases of excitatory amino acids, alterations in the genomic responses, mitochondrial injury producing reactive oxygen and nitrogen species (ROS), and secondary injury, often in the setting of reperfusion |
| Analysis |
Medicine |
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Neurosciences |
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Biomedicine |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
| Subject |
Cerebrovascular disease.
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Metal ions.
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Metals.
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Stroke -- physiopathology
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Metals
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metal.
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MEDICAL -- Neurology.
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Metals
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Cerebrovascular disease
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Metal ions
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| Form |
Electronic book
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| Author |
Li, Yang V
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Zhang, J. H. (John H.)
|
| ISBN |
9781441996633 |
|
144199663X |
|
1441996621 |
|
9781441996626 |
|
