| Description |
1 online resource (streaming video file) (369 secs.) |
| Series |
Biology |
| Summary |
Leucine Rich Repeat Kinase 2 is a large multidomain kinase, mutations in which are the most common genetic cause of Parkinson's disease. Analysis of the kinase activity of this protein has proven to be a crucial tool in understanding the biology and dysfunction of this protein. In this paper, in vitro assaying of the kinase activity of LRRK2 and a selection of its mutants is described, providing an experimental system to examine phosphorylation of putative substrates and potential dysfunction of LRRK2 in disease |
| Audience |
For undergraduate, graduate, and professional students |
| Notes |
English |
|
Description based on online resource; title from resource description page |
| Subject |
Biology
|
| Form |
Streaming audio
|
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