| Description |
1 online resource (xiv, 273 pages) : illustrations |
| Series |
Contemporary endocrinology |
|
Contemporary endocrinology (Totowa, N.J.)
|
| Contents |
pt. I. Basic stem cell biology. Embryonic stem cells: derivation, properties, and therapeutic implications / Victor L. Browning and Jon S. Odorico -- Germ line stem cells / Makoto C. Nagano -- Umbilical cord stem cells / Kathy E. Mitchell -- Differentiation potential of adult stem cells / Henry E. Young and Asa C. Black, Jr. -- Growth conditions for primate vs murine embryonic stem cells / Gillian M. Beattie [and others] -- pt. II. Translational research. Islet precursor cells in adult pancreatic islets / Gladys Teitelman and Irem Nasir -- Transcription factor-directed differentiation of stem cells along an endocrine lineage / William L. Lowe, Jr. -- Generation of islet-like structures from ES cells / Nadya Lumelsky -- The therapeutic potential of liver repopulation for metabolic or endocrine disorders / Sanjeev Gupta -- The manipulation of mesenchymal stem cells for bone repair / Shelley R. Winn -- Spermatogenesis from transplanted spermatogenic stem cells / Michael D. Griswold and Derek McLean -- Hematopoietic stem cell transplant in the treatment of autoimmune endocrine disease / Jody Schumacher and Ewa Carrier -- Preclinical trials for stem cell therapy / Linda B. Lester, K.Y. Francis Pau, and Don P. Wolf |
| Summary |
A critical review by prominent experts of both the cutting-edge of stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| Subject |
Stem cells.
|
|
Endocrinology, Experimental.
|
|
Endocrine System Diseases -- therapy
|
|
Stem Cells
|
|
MEDICAL -- Research.
|
|
Endocrinology, Experimental
|
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Stem cells
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| Form |
Electronic book
|
| Author |
Lester, Linda B
|
| ISBN |
1588294072 |
|
9781588294074 |
|
1592599001 |
|
9781592599004 |
|
1280359242 |
|
9781280359248 |
|
9786610359240 |
|
6610359245 |
|
