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E-book

Title Organ Tissue Engineering / edited by Daniel Eberli, Sang Jin Lee, Andreas Traweger
Published Cham : Springer, [2020]
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Description 1 online resource
Series Tissue engineering and regeneration
Reference series in biomedical engineering
Contents Brain Central Neural System -- Vison system, retina, cornea -- Olfactory system -- Craniomaxillofacial bone engineering -- Ear, Nose and Throat -- Dental, tooth -- Thymus, Lymphoid -- Oesophagus, Trachea -- Lung -- Gastro Intestinal Tract (Organoids) -- Kidney -- Bladder/Urethra -- Liver (Biomaterial, Cells) -- Endocrine Organs (Pancreas) -- Salivary grand -- Breast Tissue / Fat Tissue -- Ovary -- Penis -- Great Vessels -- Cell sheets for cardiac tissue engineering -- Heart valve Bioengineering -- Ligament -- Meniskus als muskuloskelettaler Abschnitt -- Tendons -- Skeletal system and Muscle
Summary The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort
Notes Publisher's index page (viewed on May 01, 2020)
In Springer Nature Living Reference
Subject Tissue engineering.
Biomedical engineering.
Regenerative medicine.
Biomedical materials.
Medical rehabilitation.
Tissue Engineering
Regenerative Medicine
Rehabilitation
biomedical engineering.
Biomedical engineering
Biomedical materials
Medical rehabilitation
Regenerative medicine
Tissue engineering
Form Electronic book
Author Eberli, Daniel, editor
Lee, Sang Jin, editor
Traweger, Andreas, editor
ISBN 9783030185121
3030185125