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Title Management of advanced prostate cancer / Choung Soo Kim, editor
Published Singapore : Springer, [2018]
©2018

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Description 1 online resource
Contents Intro; Preface; Contents; Part I: Surgery for Advanced Prostate Cancer; 1: Natural History ofHigh-Risk Prostate Cancer; 1.1 Introduction; 1.2 The Definition ofHigh-Risk Prostate Cancer; 1.3 Risk Factors forHigh-Risk Prostate Cancer; 1.4 Natural History ofHigh-Risk Prostate Cancer; 1.4.1 Localized or Locally Advanced High-Risk Prostate Cancer; 1.4.2 Hormone-Naïve Metastatic Prostate Cancer; 1.4.3 Castration-Resistant Prostate Cancer; 1.5 Summary; References; 2: Identifying theBest Candidate forRadical Prostatectomy inHigh-Risk Prostate Cancer; 2.1 Introduction
2.2 RP forHigh-Grade Cancer2.3 RP forT3/4 N0 M0 Disease; 2.4 RP forNode-Positive Disease; 2.5 The Efficacy of RP over External Beam Radiation Therapy (EBRT) withor Without ADT (Androgen Deprivation Therapy); 2.6 Safety of RP Compare toEBRT (with or Without ADT); 2.7 RP inElderly Patients; 2.8 Recent Efforts forIdentifying the Better Candidate forRP Among Patients with High-ƯRisk Prostate Cancer; 2.9 Summary; References; 3: Neoadjuvant Therapy Prior toRadical Prostatectomy; 3.1 Introduction; 3.2 Neoadjuvant Hormonal Therapy; 3.3 Neoadjuvant Chemotherapy withor Without ADT
3.4 Neoadjuvant Therapy Using Novel Medicines3.5 Summary; References; 4: Robot-Assisted Radical Prostatectomy forHigh-Risk Prostate Cancer; 4.1 Introduction; 4.2 What Is High-Risk PCa?; 4.3 RARP forHigh-Risk PCa; 4.3.1 Nerve Sparing inHigh-Risk PCa During RARP; 4.3.2 Lymph Node Dissection inHigh-Risk PCa During RARP; 4.3.3 Perioperative Morbidity During RARP; 4.4 Outcomes of RARP forHigh-ƯRisk PCa; 4.4.1 Oncologic Outcomes of RARP forHigh-Risk PCa; 4.4.2 Functional Outcomes of RARP forHigh-Risk PCa; References; 5: Pelvic Lymphadenectomy forHigh-Risk Prostate Cancer
5.1 Current Indication of Pelvic Lymphadenectomy inHigh-ƯRisk Prostate Cancer5.2 Extent of Pelvic Lymphadenectomy (Limited Vs. Extended); 5.3 Robotic Surgery and Pelvic Lymphadenectomy; 5.4 Clinical Outcome of Pelvic Lymphadenectomy; 5.5 Complication of Pelvic Lymphadenectomy; 5.6 Summary; References; 6: Adjuvant Therapy inLocally Advanced Prostate Cancer; 6.1 Introduction; 6.2 Definition; 6.3 General Guidelines by NCCN; 6.4 RP forLocally Advanced PCa; 6.5 RT inLocally Advanced PCa; 6.6 Multimodality Treatment inLocally Advanced PCa; 6.7 Adjuvant Postoperative RT
6.8 Adjuvant HT6.9 Adjuvant Chemotherapy; 6.10 Summary; References; 7: Role of Radical Prostatectomy intheManagement of Metastatic Prostate Cancer; 7.1 Classic Role of Radical Prostatectomy forPalliative Local Symptom Control; 7.2 Feasibility of Radical Prostatectomy inMetastatic Prostate Cancer; 7.3 Possible Rationale forCytoreductive Radical Prostatectomy inMetastatic Prostate Cancer; 7.4 Indirect Evidence Supporting the Effectiveness of Cytoreductive Radical Prostatectomy
Summary This textbook summarizes the state of the art in the management of locally advanced and metastatic prostate cancer with the aim of providing the knowledge required for optimal treatment decision making in individual cases. Readers will find comprehensive coverage of the latest developments in surgery, radiotherapy, androgen deprivation therapy (ADT), chemotherapy, and immunotherapy. The role of the hormonal therapies abiraterone and enzalutamide and docetaxel-based chemotherapy in castration-resistant prostate cancer and hormone-sensitive metastatic disease is carefully evaluated. Among the other therapies discussed are LHRH agonists and antagonists, cabazitaxel, radium-223, and various novel agents still under clinical trials. The section on surgical approaches addresses, among other topics, the use of robot-assisted radical prostatectomy, pelvic lymphadenectomy, and the benefits of adjuvant and neoadjuvant therapy. The current role of external beam radiotherapy, alone or in combination with ADT and brachytherapy, for locally advanced disease is reviewed. Management of Advanced Prostate Cancer will be a valuable resource for practitioners at all levels of expertise
Bibliography Includes bibliographical references
Notes Vendor-supplied metadata
Subject Prostate -- Cancer.
Prostatic Neoplasms
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Prostate -- Cancer
Form Electronic book
Author Kim, Choung Soo, editor
ISBN 9789811069437
9811069433
9811069425
9789811069420