Description |
1 online resource (x, 1022 pages) : illustrations |
Series |
Contemporary diabetes |
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Contemporary diabetes.
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Contents |
1. Laboratory Assessment of Lipoproteins in Diabetes / Barry Lewis -- 2. Lipoprotein Subclasses and Cardiovascular Disease Risk in Insulin-Resistant Diabetes / Eliot A. Brinton -- 3. Insulin Resistance and Atherosclerosis / Vasudevan A. Raghavan -- 4. Apoproteins and Cell Surface Receptors Regulating Lipoprotein Metabolism in the Setting of Type 2 Diabetes / Thomas D. Dayspring -- 5. Lipoprotein Metabolism and Alterations Induced by Insulin Resistance and Diabetes / Daphne Owens -- 6. Production and Metabolism of Triglyceride-Rich Lipoproteins in Both the Normal and Diabetic States / Alberico L. Catapano -- 7. Lipoprotein(a): Structure, Metabolism, and Pathophysiology / Gerhard M. Kostner -- 8. Lipoprotein Glycation in Diabetes Mellitus / Andrzej S. Januszewski -- 9. Lipoprotein (LDL and HDL) Oxidation in Diabetes Mellitus / Tony Hayek |
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10. The Role of Modified Forms of LDL and Corresponding Autoantibodies in the Development of Complications in Diabetes / Gabriel Virella -- 11. Lipid: Extracellular Matrix Interactions as Therapeutic Targets in the Atherosclerosis of Diabetes / Peter J. Little -- 12. Tools for Assessing Lipoprotein Metabolism in Diabetes Mellitus / Richard L. Klein -- 13. Endothelial Dysfunction and Dyslipidemia in Type 2 Diabetes: Pathogenesis, Significance and Therapy / Gerald F. Watts -- 14. Lipoproteins and Diabetic Nephropathy / Per-Henrik Groop -- 15. Roles of Extravasated and Modified Plasma Lipoproteins in Diabetic Retinopathy / Timothy J. Lyons -- 16. Effects of Lifestyle (Diet, Plant Sterols, Exercise) and Glycemic Control on Lipoproteins in Diabetes / Peter Clifton -- 17. About Randomised Clinical Trials Related to Lipoproteins in Diabetes Mellitus / Val Gebski |
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18. Statin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients / Steven R. Jones -- 19. The PPAR System in Diabetes / Christelle Foucher -- 20. Fibrate Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients / Eliot A. Brinton -- 21. Niacin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients / James A. Underberg -- 22. Cholesterol Absorption Inhibitors (Ezetimibe) and Bile Acid Binding Resins (Colesevelam HCl) as Therapy for Dyslipidemia in Patients with Diabetes Mellitus / Harold Bays -- 23. Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes / Alicia J. Jenkins |
Summary |
Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed. An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes |
Notes |
Includes index |
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Print version record |
In |
Springer eBooks |
Subject |
Diabetes.
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Diabetes -- Molecular aspects
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Lipoproteins.
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Diabetes Mellitus
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Lipoproteins
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Médecine.
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Diabetes
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Diabetes -- Molecular aspects
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Lipoproteins
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Form |
Electronic book
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Author |
Jenkins, Alicia J., editor.
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Toth, Peter P., editor
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Lyons, Timothy J., editor.
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ISBN |
9781461475545 |
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1461475546 |
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