| Description |
1 online resource (x, 285 pages) : illustrations (some color) |
| Series |
Methods in molecular biology, 1940-6029 ; volume 1617 |
|
Methods in molecular biology (Clifton, N.J.) ; v. 1617. 1064-3745
|
| Contents |
MicroRNAs, long noncoding RNAs, and their functions in human disease / Min Xue, Ying Zhuo, and Bin Shan -- MicroRNA expression : protein participants in microRNA regulation / Valeria M. King and Glen M. Borchert -- Viral microRNAs, host microRNAs regulating viruses, and bacterial microRNA-like RNAs / Sara-Elizabeth Cardin and Glen M. Borchert -- MicroRNAs : biomarkers, diagnostics, and therapeutics / Weili Huang -- Relational databases and biomedical big data / N.H. Nisansa D. de Silva -- Semantic technologies and bio-ontologies / Fernando Gutierrez -- Genome-wide analysis of microRNA-regulated transcripts / David Chevalier and Glen M. Borchert -- Computational prediction of microRNA target genes, target prediction databases, and web resources / Justin T. Roberts and Glen M. Borchert -- Exploring microRNA : target regulatory interactions by computing technologies / Yue Hu, Wenjun Lan, and Daniel Miller -- Limitations of existing approaches in improving microRNA target prediction accuracy / Rasiah Loganantharaj and Thomas A. Randall -- Genomic regulation of microRNA expression in disease development / Feng Liu -- Next-generation sequencing for microRNA expression profile / Yue Hu, Wenjun Lan, and Daniel Miller -- Handling high-dimension (high-feature) microRNA data / Yue Hu, Wenjun Lan, and Daniel Miller -- Effective removal of noisy data via batch effect processing / Ryan G. Benton -- Logical reasoning (inferencing) on microRNA data / Jingsong Wang -- Machine learning techniques in exploring microRNA gene discovery, targets, and functions / Sumi Singh, Ryan G. Benton, Anurag Singh, and Anshuman Singh -- Involvement of microRNAs in diabetes and its complications / Bin Wu and Daniel Miller -- MicroRNA regulatory networks as biomarkers in obesity : the emerging role / Lihua Zhang, Daniel Miller, Qiuping Yang, and Bin Wu -- Expression of microRNAs in thyroid carcinoma / Gaohong Zhu, Lijun Xie, and Daniel Miller |
| Summary |
This thorough volume provides an in-depth introduction to and discussion of microRNAs (miRs) and their targets, miR functions, and computational techniques applied in miR research, thus serving the need for a comprehensive book focusing on miR target genes, miR regulation mechanisms, miR functions performed in various human diseases, and miR databases/knowledgebases. Without prior knowledge of the area of study, computational biologists, computer scientists, bioinformaticians, bench biologists, as well as clinical investigators will find it easy to follow the techniques in this collection. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that ensures successful results. Accessible and practical, Bioinformatics in MicroRNA Research functions as an ideal guide for researchers of all backgrounds to explore this vital area of study |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Includes index |
|
Online resource; title from PDF title page (SpringerProtocols, viewed May 26, 2017) |
| Subject |
MicroRNA -- Laboratory manuals
|
|
Bioinformatics -- Laboratory manuals
|
|
MicroRNA.
|
|
Computational Biology -- methods
|
|
MicroRNAs
|
|
Molecular biology.
|
|
Science -- Life Sciences -- Anatomy & Physiology.
|
|
Bioinformatics
|
|
MicroRNA
|
| Genre/Form |
Laboratory manuals
|
|
Laboratory manuals.
|
|
Manuels de laboratoire.
|
| Form |
Electronic book
|
| Author |
Huang, Jingshan, editor.
|
|
Borchert, Glen M., editor
|
|
Dou, Dejing, editor
|
|
Huan, Jun, 1975- editor.
|
|
Lan, Wenjun, editor
|
|
Tan, Ming, editor.
|
|
Wu, Bin, editor
|
| LC no. |
2017937362 |
| ISBN |
9781493970469 |
|
1493970461 |
|
1493970445 |
|
9781493970445 |
|
