Description |
1 online resource (314 pages) |
Contents |
Intro -- Preface -- Contents -- Contributors -- Chapter 1: Coagulation and Anticoagulants -- Introduction -- The Coagulation Cascade -- Cell-Based Model of Hemostasis -- Natural Anticoagulants, Predisposing Factors, and Exposing Factors of Clot Formation -- Anticoagulants -- Injectable Indirect Thrombin/Anti-Xa Inhibitors -- Unfractionated Heparin (UFH) -- Historic Background -- Route and Dose -- Therapeutic -- Prophylactic -- Side Effects -- Contraindications -- Reversal -- Low-Molecular-Weight Heparins [LMWHs] -- Indications and Dosage [39-46] -- Warning and Precautions -- Monitoring |
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Pentasaccharide -- Fondaparinux -- Indication and Dose -- Deep Vein Thrombosis Prophylaxis Following Hip Fracture, Hip Replacement, and Knee Replacement Surgery -- Deep Vein Thrombosis Prophylaxis Following Abdominal Surgery -- Deep Vein Thrombosis Prophylaxis in Medical Patients -- Deep Vein Thrombosis and Pulmonary Embolism Treatment, Including HIT -- Acute Coronary Syndrome -- Warnings and Precautions -- Vitamin K Antagonists [VKAs] and Warfarin -- Warfarin -- Historic Background -- Bioavailability and Half-Life -- Formulation -- Dose and Administration -- Warfarin Resistance |
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Warfarin Interactions -- Food, Food Supplement, and Herbal Interactions -- Other Interactions -- Drug Interactions [69-73] -- Contraindications -- Adverse Events -- Injectable Direct Thrombin Inhibitors -- Hirudins -- Bivaluridin -- Argatroban [103-106] -- NOACs/DOACs -- Contraindications -- NOACs Include -- Oral Direct Thrombin Inhibitor: Dabigatran -- Indications -- Dose -- Contraindications [110] -- Risk of Bleeding -- Drug Interactions [110] -- Other Drugs -- Impact of Dabigatran on Other Drugs -- Conversion to Warfarin [110] -- Converting from or to Parenteral Anticoagulants |
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Oral Direct Factor Xa Inhibitors -- Apixaban [112] -- Formulation -- Indications -- Contraindications [112] -- Dose -- Precautions in Special Populations [112] -- Renal Impairment -- Hepatic Impairment -- Concomitant Use of Antiplatelet Agents -- Drug Interactions [112] -- Switching from to and from Other Anticoagulation Agents -- Switching from or to Parenteral Anticoagulants -- Switching from VKA to Apixaban -- Switching from Apixaban to VKA -- Anticoagulation Bridging (See Chap. 12) -- Betrixaban [121] -- Formulation -- Indications -- Dose -- Precautions -- Side Effects and Bleeding Risks |
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Bleeding Reversal -- Edoxaban [123] -- Formulation -- Indications -- Contraindications [123, 126] -- Precautions [123] -- Drug Interactions: [120] -- Switching Between Agents [123] -- Bridging Anticoagulation (Please refer to Chap. 12) -- Rivaroxaban [129] -- Formulation -- Indications -- Dose -- Precautions and Bleeding Risks -- Switching from One Anticoagulant to Another -- Switching from Parenteral Anticoagulants to Rivaroxaban -- Switching from Rivaroxaban to Parenteral Anticoagulants -- Switching from Vitamin K Antagonists (VKAs) to Rivaroxaban -- Switching from Rivaroxaban to a VKA |
Summary |
This book provides a practical guide to the use of novel and conventional anticoagulants for a variety of medical conditions and patients profiled. It reviews data for selecting the most appropriate medication for a given presentation based on a patient's background while highlighting current best practices. Chapters discuss the choice of agents and optimum duration of therapy while including the relevant literature review and evidence. Specific sections focus on the use of anticoagulants in patients with cardiovascular disease, autoimmune and rheumatologic disorders, antiphospholipid syndrome, cancer, and in the surgical contexts. The book also examines anticoagulation in pregnant and lactating women, pediatric and elderly populations, and patients with extreme weights. Intended for use in daily practice, Precision Anticoagulation Medicine - A Practical Guide is an essential resource for physicians and related professionals, residents, fellows, and graduate students in hematology, cardiology, rheumatology, oncology, surgery, anesthesiology, and intensive care |
Notes |
Anticoagulation Bridging: See Chap. 12 |
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Includes index |
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Print version record |
Subject |
Anticoagulants (Medicine)
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Blood -- Coagulation.
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Anticoagulants
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Blood Coagulation
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Anticoagulants (Medicine)
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Blood -- Coagulation
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Form |
Electronic book
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Author |
Goubran, Hadi
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Ragab, Gaafar.
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Hassouna, Suzy
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ISBN |
9783030257828 |
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3030257827 |
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