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Book Cover
Author Stanbury, Peter F.

Title Principles of fermentation technology / Peter F. Stanbury, Allan Whitaker, Stephen J. Hall
Edition Third edition
Published Oxford, U.K. ; Cambridge, MA : Elsevier Butterworth-Heinemann, [2017]
Online access available from:
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Description 1 online resource (826 pages)
Contents Comparison of batch and continuous culture in industrial processesBiomass productivity; Metabolite productivity; Continuous brewing; Continuous culture and biomass production; Comparison of batch and continuous culture as investigative tools; Fed-batch culture; Variable volume fed-batch culture; Fixed volume fed-batch culture; Fed-batch culture at a constant specific growth rate; Cyclic fed-batch culture; Application of fed-batch culture; Examples of the use of fed-batch culture; References; Chapter 3 -- The isolation and improvement of industrially important microorganisms
Cover; Title Page; Copyright Page; Dedication; Contents; Acknowledgments; Chapter 1 -- An introduction to fermentation processes; The range of fermentation processes; Microbial biomass; Microbial enzymes; Microbial metabolites; Recombinant products; Transformation processes; The chronological development of the fermentation industry; The component parts of a fermentation process; References; Chapter 2 -- Microbial growth kinetics; Batch culture; Exponential phase; Deceleration and stationary phases; Continuous culture; Multistage systems; Feedback systems; Internal feedback; External feedback
Isolation of industrially important microorganismsIsolation methods utilizing selection of the desired characteristic; Enrichment liquid culture; Enrichment cultures using solidified media; Isolation methods not utilizing selection of the desired characteristic-from the "Waksman platform" to the 1990s; Screening methods and high throughput screening; Return of natural products; Broadening the base of the discovery process and maximizing gene expression; Improvement of industrial microorganisms; Improvement of strains producing primary biosynthetic products
Postgenomic era-the influence of genomics, transcriptomics, and fluxomics on the improvement of primary metabolite producersApplication of genomics; Application of transcriptomics; Application of metabolic flux analysis and a systems biology approach; Improvement of strains producing secondary biosynthetic products; Isolation of mutants producing improved yields of secondary metabolites; The empirical approach; Use of directed selection in the isolation of improved secondary metabolite producers; Use of recombination systems for the improvement of secondary metabolite production
Selection of induced mutants synthesizing improved levels of primary metabolitesIsolation of Corynebacterium glutamicum and the role of permeability in the glutamate fermentation; Isolation of mutants that do not produce feedback inhibitors or repressors; Isolation of mutants that do not recognize the presence of inhibitors and repressors; The use of recombination systems for the improvement of primary metabolite production; Transduction, transformation, and protoplast fusion; Recombinant DNA technology
Notes The application of the parasexual cycle
Bibliography Includes bibliographical references and index
Notes Online resource; title from digital title page (viewed on Nov. 17, 2016)
Subject Fermentation.
Form Electronic book
Author Hall, Stephen J. (College teacher)
Whitaker, Allan.
ISBN 0444634088 (electronic bk.)
9780444634085 (electronic bk.)