| Description |
1 online resource (679 p.) |
| Contents |
Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Preface -- Foreword -- Chapter 1: Introduction to Cancer, Conventional Therapies, and Bionano-Based Advanced Anticancer Strategies -- 1.1: Cancer -- 1.2: Understanding Cancer and Its Occurrence -- 1.2.1: Genes Activities Related to Cancer -- 1.3: Different Theories of Carcinogenesis -- 1.4: Factors Influencing Cancer Development -- 1.4.1: Intrinsic/Biological Factors -- 1.4.2: External Factors -- 1.5: Microenvironment of Cancer -- 1.5.1: Tumor Angiogenesis -- 1.5.2: Physical and Chemical Cues -- 1.5.3: Acidosis |
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1.5.4: High Interstitial Fluid Pressure -- 1.5.5: Enhanced Permeability Retention -- 1.5.6: Hypoxia -- 1.6: Cellular and Non-Cellular Components That Support Tumor Growth -- 1.6.1: Cellular Components -- 1.6.2: Non-Cellular Components -- 1.7: Difference between Normal Cells and Cancer Cells -- 1.8: Conventional Anti-Cancer Therapies -- 1.9: Cell Death and Cancer -- 1.10: Advanced Nanotechnology for Cancer Diagnosis and Therapy -- 1.10.1: Key Features of Nanomaterials for Therapy and Diagnostic Applications -- 1.10.1.1: Nanoparticle size -- 1.10.1.2: Nanoparticle surface properties |
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1.10.1.3: NPs in diagnosis -- 1.10.1.4: NPs in imaging -- 1.10.1.5: Targeted nanoparticles -- 1.10.1.6: Nanomaterials to target and regulate tumor and its microenvironment -- 1.10.2: Challenges Faced by NPs in Combatting Tumor -- 1.10.2.1: Challenges faced during circulation -- 1.10.2.2: Challenges after reaching tumor -- 1.11: Conclusion and Future Perspective -- Chapter 2: Understanding the Interaction of Nanoparticles at the Cellular Interface -- 2.1: Introduction -- 2.2: Nanotechnology -- 2.3: NPs and Cell Internalization -- 2.4: Transmembrane Penetration by Designed Nanomaterials |
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2.5: Engineered Protein Corona: A Better Drug Delivery System -- 2.6: Subcellular Interaction of NPs -- 2.7: Endosomal/Lysosomal Escape of NPs -- 2.7.1: Formation of Membrane Pores in Lysosomes/Endosomes -- 2.7.2: Proton Sponge Effect -- 2.7.3: Fusion with Endosomal Membrane -- 2.7.4: Photochemical Rupture of Endosomal Membrane -- 2.8: Tumor and Nanomedicine -- 2.9: Smart Material as Drug Delivery Nanoparticle -- 2.9.1: Polymeric Drug Nanocarrier: Act as a Smart Material -- 2.10: Conclusion and Future Perspective -- Nanodiagnostics -- Chapter 3: Radiolabeled Nanoparticles for Cancer Diagnosis |
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3.1: Introduction -- 3.2: SPECT -- 3.3: Positron Emission Tomography -- 3.4: Radiolabeled Nanoparticles -- 3.4.1: Polymer-Based RNPs -- 3.4.2: Liposome-Based RNPs -- 3.4.3: Carbon Nanotube-Based RNPs -- 3.4.4: Inorganic NPs as RNPs -- 3.5: Multimodal Imaging of PET and SPECT with MRI, CT, and NIRF -- 3.6: Conclusion and Future Prospects -- Chapter 4: Magnetic Nanoparticles for Cancer Diagnosis -- 4.1: Introduction -- 4.2: Principle of MRI -- 4.3: MNPs as MRI Contrast Agents -- 4.4: Dual-Mode (T1 and T2) MRI Contrast Agents -- 4.5: Multimodal Imaging: MRI with PET, SPECT, Optical, and Ultrasound |
| Notes |
Description based upon print version of record |
|
4.6: Novel Application of MNPs for Imaging |
| Form |
Electronic book
|
| Author |
Girija, Aswathy Ravindran
|
| ISBN |
9780429750410 |
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0429750412 |
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