| Description |
1 online resource (x, 215 pages) : illustrations (some color) |
| Series |
Current Topics in Microbiology and Immunology, 0070-217X ; volume 377 |
|
Current topics in microbiology and immunology ; v. 377. 0070-217X
|
| Contents |
High Dimensional Single Cell Cancer Biology -- Studying the Human Immunome: The Complexity of Comprehensive Leukocyte Immunophenotyping -- High-dimensional Analysis of Human CD8+ T Cell Phenotype, Function and Antigen-Specificity -- Mass Cytometry to Decipher the Mechanism of Non-genetic Drug Resistance in Cancer -- A Practical Guide to Multiplexed Mass Cytometry -- Analysis of Protein Interactions in situ by Proximity Ligation Assays -- Cytobank: Providing an Analytics Platform for Community Cytometry Data Analysis and Collaboration -- Computational Analysis of High-Dimensional Flow Cytometric Data for Diagnosis and Discovery -- Shooting Movies of Signaling Network Dynamics with Multiparametric Cytometry -- Hyperspectral Cytometry |
| Summary |
This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques for the analysis of data sets involving dozens of parameters in millions of single cells. Topics include single cell cancer biology; studies of the human immunome; exploration of immunological cell types such as CD8+ T cells; decipherment of signaling processes of cancer; mass-tag cellular barcoding; analysis of protein interactions by proximity ligation assays; Cytobank, a platform for the analysis of cytometry data; computational analysis of high-dimensional flow cytometric data; computational deconvolution approaches for the description of intracellular signaling dynamics; and hyperspectral cytometry. All 10 chapters of this book have been written by respected experts in their fields. It is an invaluable reference book for both basic and clinical researchers |
| Notes |
Includes index |
|
Online resource; title from PDF title page (SpringerLink, viewed May 6, 2014) |
| Subject |
Cytometry.
|
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Bioinformatics.
|
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Computational biology.
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Flow Cytometry -- methods
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Computational Biology
|
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SCIENCE -- Life Sciences -- Anatomy & Physiology.
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Bioinformatics
|
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Computational biology
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Cytometry
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| Form |
Electronic book
|
| Author |
Fienberg, Harris G., editor
|
|
Nolan, Garry P., editor.
|
| ISBN |
9783642548277 |
|
364254827X |
|
3642548261 |
|
9783642548260 |
|
