| Description |
1 online resource |
| Contents |
Cover; Title Page; Copyright; Contents; Contributors; Preface; Chapter 1 The History of Fish Vaccination; 1.1 Introduction; 1.2 Aquaculture; 1.3 Immunology; 1.4 Disease Prevention; 1.5 Scientific Production-Reviews and Conferences; 1.5.1 Salmonids; 1.5.2 Non-salmonids; 1.6 Successes and Failures; 1.7 The Pioneers; 1.8 Concluding Remarks; References; Chapter 2 Vaccination as a Preventive Measure; 2.1 Introduction; 2.2 Biosecurity and Vaccination; 2.3 Use of Vaccination in Aquaculture; 2.4 Vaccination Against Different Diseases; 2.5 Herd Immunity; 2.6 Economic Considerations |
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2.7 Risk Assessment2.8 The Market for Fish Vaccines; References; Chapter 3 Non-replicating Vaccines; 3.1 Introduction; 3.2 Classification; 3.2.1 Inactivated vaccines; 3.2.2 Subunit vaccines; 3.2.3 Synthetic peptide vaccines; 3.2.4 Particulate vaccines; 3.3 Inactivated Vaccines-Methods of Inactivation; 3.3.1 Physical inactivation; 3.3.2 Chemical inactivation; 3.4 Evaluation of Inactivation Efficacy; 3.5 Measures of Efficacy for Inactivated Vaccines; 3.5.1 Relative percent survival (RPS); 3.6 Mechanisms of Vaccine Protection; 3.7 Antibodies as Correlates of Protective Immunity |
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3.8 Antigen Dose as Correlate of Protective ImmunityReferences; Chapter 4 Replicating Vaccines; 4.1 Introduction; 4.2 Attenuation Strategies-Bacterial Vaccines; 4.2.1 Laboratory passage; 4.2.2 Environmental bacterium; 4.2.3 Physical or chemical mutagenesis; 4.2.4 Genetic modification; 4.2.5 Vaccination with live recombinant organisms expressing bacterial antigen; 4.3 Attenuation Strategies-Viral Vaccines; 4.3.1 Laboratory passage; 4.3.2 Molecular techniques; 4.4 Induction of Immunity; 4.5 Vaccine Delivery; 4.6 Vaccine Safety Considerations; 4.7 Acknowledgement; References |
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Chapter 5 DNA Vaccines5.1 Introduction; 5.2 Comparison of DNA Vaccines with Conventional Inactivated Products: Advantages and Disadvantages; 5.2.1 Development of test vaccines; 5.2.2 Production and storage; 5.2.3 Formulation and delivery; 5.3 DNA Vaccines for Veterinary Use; 5.4 Biosecurity and Regulatory Considerations; References; Chapter 6 Mucosal Vaccination of Fish; 6.1 Introduction; 6.2 History of ""Mucosal'' Vaccination; 6.3 Mucosal versus Systemic Immunity in Fish; 6.4 Immersion Vaccination; 6.5 Oral Vaccination; 6.5.1 Oral vaccination with unprotected antigens; 6.5.2 Bioencapsulation |
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6.5.3 Edible vaccines6.5.4 Microbial biofilms; 6.5.5 Microencapsulation; 6.5.6 Alternative methods; 6.6 Perspectives; References; Chapter 7 Adjuvants in Fish Vaccines; 7.1 Introduction; 7.2 Vaccine Formulations; 7.3 Principles of Adjuvant Actions; 7.4 Antigenic Component; 7.5 Adjuvants; 7.6 Antigen Delivery Systems; 7.7 Delivery Vehicles; 7.8 Emulsion Vaccines; 7.8.1 Oil-adjuvant vaccines; 7.8.2 Particle-based/formulated vaccines; 7.9 Biodegradable Particulate Delivery Systems; 7.10 Fusion Protein Delivery System; 7.11 Immunomodulators; 7.11.1 Aluminum-containing adjuvants; 7.11.2 Saponins |
| Summary |
Fish farming, in seawater and in freshwater, in cages, tanks or ponds, makes an ever-increasing and significant contribution to the production of aquatic food in many regions of the world. During the last few decades there has been significant progress and expansion in the aquaculture sector, characterized by intensified production and the exploitation of many new species. Aquaculture must be a sustainable bio-production, environmentally as well as economically. Disease prevention in order to reduce losses, and the use of antimicrobials is crucial in this perspective. Vaccination has, in a few years, become the most important method for disease prevention in aquaculture, and effective prophylaxis based on stimulation of the immune system of the fish is essential for further development of the industry |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record and CIP data provided by publisher |
| Subject |
Fishes -- Vaccination
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Fishes -- Diseases -- Prevention
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SCIENCE -- Life Sciences -- Anatomy & Physiology.
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Fishes -- Diseases -- Prevention
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| Form |
Electronic book
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| Author |
Gudding, Roar
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Lillehaug, Atle, 1954-
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Evensen, Øystein, 1959-
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| LC no. |
2013035433 |
| ISBN |
9781118806937 |
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111880693X |
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9781118806920 |
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1118806921 |
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9781118806913 |
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1118806913 |
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0470674555 |
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9780470674550 |
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9781306473644 |
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1306473640 |
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