| Description |
1 online resource (xii, 390 pages) : illustrations |
| Contents |
Front cover; Contents; Editor's preface; Preface; Grieves Harnby: In memoriam; 1 Introduction; 2 The importance of the physicochemical properties of drugs to drug metabolism; 3 Sample preparation; 4 High-performance liquid chromatography in pharmaceutical bioanalysis; 5 Mass spectrometry and quantitative bioanalysis; 6 Immunoassay in pharmacokinetic and pharmacodynamic bioanalysis; 7 Pre-clinical pharmacokinetics; 8 Pharmacokinetic/ pharmacodynamic modelling in pre-clinical drug discovery; 9 Toxicokinetics; 10 Protein binding in plasma: a case history of a highly protein-bound drug |
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11 Isotope drug studies in man12 Whole body autoradiography; 13 Phase I metabolism; 14 Phase II enzymes; 15 In vitro tecniques for investigating drug metabolism; 16 Drug-drug interactions: an in vitro approach; 17 Identification of drug metabolites in biological fluids using qualitative spectroscopic and chromatographic techniques; 18 Molecular biology; 19 The role of drug metabolism and pharmacokinetics in drug discovery: past, present and future; Index; Back cover |
| Summary |
Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting - until now. A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and developme |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
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Print version record |
| Subject |
Drugs -- Analysis.
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Drugs -- Metabolism -- Research -- Methodology
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Pharmacokinetics -- Research -- Methodology
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Pharmaceutical industry.
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Pharmacokinetics.
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Pharmaceutical Preparations -- metabolism
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Chemistry Techniques, Analytical
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Drug Industry
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Pharmacokinetics
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MEDICAL -- Drug Guides.
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MEDICAL -- Pharmacology.
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MEDICAL -- Pharmacy.
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MEDICAL -- Nursing -- Pharmacology.
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Pharmacokinetics
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Pharmaceutical industry
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Drugs -- Analysis
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Pharmacokinetics -- Research -- Methodology
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| Genre/Form |
handbooks.
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Handbooks and manuals.
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Guides et manuels.
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| Form |
Electronic book
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| Author |
Evans, Gary, 1953-
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| ISBN |
0203642538 |
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9780203642535 |
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