| Description |
1 online resource (xvi, 399 pages) : illustrations (some color) |
| Contents |
Evolution-based genome analysis: an alternative to analyze folding and function in proteins / Steven Benner -- Conformation of charged polymers: polyelectrolytes and polyampholytes / Jean-François Joanny -- Statistically derived rules for RNA folding / Michael Zuker -- Experimental approaches to RNA folding / Sarah Woodson -- Some questions concerning RNA folding / François Michel -- RNA folding in ribosome assembly / James R. Williamson -- From RNA sequences to folding pathways and structures: a perspective / Hervé Isambert -- An evolutionary perspective on the determinants of protein function and assembly / Olivier Lichtarge -- Some residues are more equal than others: application to protein classification and structure prediction / Alexander Kister and Izrail Gelfand -- Structure-function relationships in polymerases / Marc Delarue -- The protein-folding nucleus: from simple models to real proteins / Leonid Mirny -- Chaperonin-mediated protein folding / Devarajan Thirumalai -- Virus assembly and maturation / John E. Johnson -- The animal in the machine: is there a geometric program in the genetic program? / Antoine Danchin |
| Summary |
Organized by Alessandra Carbone (IHÉS, Bures-sur-Yvette, France), Misha Gromov (IHÉS, Bures-sur-Yvette, France), François Képès (CNRS-Genopole®, Évry, France), Eric Westhof (Université Louis-Pasteur, Strasbourg, France). This proceedings volume explores the pathways and mechanisms by which constituent residues interact and fold to yield native biological macromolecules (catalytic RNA and functional proteins), how ribosomes and other macromolecular complexes self-assemble, and relevant energetics considerations. At the week-long interactive conference, some 20 leading researchers reported their most pertinent results, confronting each other and an audience of more than 150 specialists from a wide range of scientific disciplines, including structural and molecular biology, biophysics, computer science, mathematics, and theoretical physics. The fourteen papers - and audience interaction - are edited and illustrated versions of the transcribed oral presentations |
| Bibliography |
Includes bibliographical references |
| Notes |
English |
|
Print version record |
| Subject |
Macromolecules -- Congresses
|
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Macromolecular Substances
|
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Protein Folding
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Nucleic Acid Conformation
|
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SCIENCE -- Chemistry -- Organic.
|
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Macromolecules.
|
| Genre/Form |
Conference papers and proceedings.
|
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Conference papers and proceedings.
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Actes de congrès.
|
| Form |
Electronic book
|
| Author |
Westhof, Eric.
|
|
Hardy, N. (Noah)
|
| LC no. |
2005297873 |
| ISBN |
9789812703057 |
|
9812703055 |
|
1281899054 |
|
9781281899057 |
|
9786611899059 |
|
6611899057 |
|
