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Title High altitude medicine : a case-based approach / Jorge Hidalgo, Sabrina Da Re, António Gandra D'Almeida, editors
Published Cham : Springer, 2023

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Description 1 online resource
Contents Intro -- Foreword -- Acknowledgments -- Contents -- Chapter 1: Introduction to High Altitude Medicine -- Objectives -- Case Study -- Discussion of the Case -- Pathogeny -- Clinic -- AMS Clinic -- HACE Clinic -- HAPE Clinic -- Diagnosis -- AMS Diagnosis -- HACE Diagnosis -- HAPE Diagnosis -- Differential Diagnosis (DD) -- AMS DD -- HACE DD -- HAPE DD -- Treatment -- AMS and HACE Treatment -- HAPE Treatment -- Prevention -- AMS/HACE Preventive -- HAPE Preventive -- Question Discussion -- References -- Chapter 2: History of High Altitude Medicine -- HAPE -- Introduction
History of High-Altitude Medicine -- Soroche and Puna -- Ballooning and High Altitude -- Exploring the Everest -- Conquering the Height Without Oxygen -- The "Great and the Little Headache" -- How Can You Identify with Acute Mountain Sickness Headache? -- Conclusion -- References -- Chapter 3: Genetics in High Altitude Medicine -- Case Scenario -- Introduction -- Role of Genetics in High Altitude Adaptation -- Hypoxia Inducible Factor Pathway -- Genes Identified in High Altitude Adaptations -- Conclusion -- References
Chapter 4: High Altitude Medicine, Its Relevance and Classification According to Meters -- Introduction -- Definition [3, 4] -- Environment Considerations -- References -- Chapter 5: Physiology of High-Altitude Illness -- Case Presentation -- Principles of Hypobaric Hypoxia and Its Physiology -- Overview -- Acclimatization -- Respiratory Changes -- Renal Changes -- Cardiovascular Changes -- Hematologic Changes -- Evidence Contour -- Rate of Ascent -- Preaclimatization -- Alcohol, Sedative/Hypnotics, and Acclimatization -- Diet and Altitude -- Exercise -- References
Chapter 6: Acid-Base Homeostasis at the High Altitude -- Normal ABG Values at High Altitude -- Acclimatization in Lowlanders Visiting High Altitudes -- What If Acclimatization Is Inadequate? -- Can Acid-Base Changes and Acclimatization Be Predicted? -- References -- Chapter 7: Cardiovascular Changes in High Altitude -- Case Scenario -- What Is the Diagnosis and Underlying Pathophysiology? -- What Is Acute High Altitude Hypoxia (HAH) and the Cardiovascular Response? -- The Cardiac System -- The Pulmonary Vascular System -- High Altitude Pulmonary Edema (HAPE) -- The Cerebro-Vascular System
High Altitude Cerebral Edema (HACE) -- What Are the Long Term Adaptations at High Altitude? -- The Cardiac System -- The Pulmonary Vascular System -- Conclusion -- References -- Chapter 8: Peripheral Tissue in High Altitude -- Introduction -- Acute Adjustments -- Acclimatization -- Acclimatization to High Altitude -- Systemic Circulation -- Pulmonary Circulation -- Cerebral Circulation -- Hematopoietic Responses to Altitude -- Oxyhemoglobin Dissociation Curve -- Tissue Changes -- Physiologic Changes during Acclimatization to Maintain Tissue Oxygen (O2) Delivery
Summary High-altitude illness is a collective term for a cluster of acute clinical syndromes that directly consequence from rapid ascent to high altitude, viz., above 2500 m. The acute syndromes affecting the brain include acute mountain sickness (AMS) and high-altitude cerebral edema (HACE). The current practice of high altitude medicine requires a deep knowledge of existing evidence. However, knowledge of the field is continuously evolving, and there are many gaps in the existing literature as well as areas of controversy despite existing research in the area. Each chapter begins with a real case from the author's clinical practice. After each case, a question is asked to allow the reader to reflect on clinical management before reading the answer and consolidating knowledge from experts in the field. They also focus on the standard practice of management and diagnosis, emphasizing evidence-based care when available as well as areas of uncertainty and active debate in the medical literature. Written by experts in the field, High Altitude Medicine offers the most up-to-date knowledge about high altitude medicine that is not only useful for physicians at high altitude dedicated centers but also medical providers at different levels of their careers, especially emergency and urgent care physicians who are the ones that initially see the patient.
Notes Online resource; title from PDF title page (Springer, viewed September 14, 2023)
Subject Mountain sickness.
Altitude, Influence of.
Altitude Sickness
Critical care medicine
Family medicine
Form Electronic book
Author Hidalgo, Jorge.
Da Re, Sabrina
D'Almeida, António Gandra
ISBN 9783031350924
3031350928