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Title IGF-I and IGF binding proteins : basic research and clinical management / volume editors, Stefano Cianfarani, David R. Clemmons, Martin O. Savage
Published Basel ; New York : Karger, 2005


Description 1 online resource (ix, 175 pages) : illustrations
Series Endocrine development, 1421-7082 ; v. 9
Endocrine development ; v. 9. 1421-7082
Contents The IGF system: new developments relevant to pediatric practice / Rosenfeld, R.G. -- Clinical relevance of systemic and local IGF-I / Yakar, S. [and others] -- Cartilage disorders: potential therapeutic use of mesenchymal stem cells / Spagnoli, A., Longobardi, L., O'Rear, L. -- Treatment in animal models / Guan, J. [and others] -- Insulin-like growth factor-I and risk of type 2 diabetes and coronary heart disease: molecular epidemiology / Sandhu, M.S. -- Quantitative measurement of IGF-I and its use in diagnosing and monitoring treatment of disorders of growth hormone secretion / Clemmons, D.R. -- IGF-I and IGFBP-3 assessment in the management of childhood onset growth hormone deficiency / Cianfarani, S., Liguori, A., Germani, D. -- IGFs and IGFBPs in clinical management of adult growth hormone deficiency / Aimaretti, G. [and others] -- Monitoring of insulin-like growth factors during growth hormone treatment: adulthood growth hormone deficiency / Monson, J.P. -- IGFs and IGFBPs in clinical management: GH insensitivity / Savage, M.O. [and others] -- Childhood and adol[e]scent diabetes / Dunger, D.B., Regan, F.M., Acerini, C.L. -- Insulin resistance and type 2 diabetes mellitus: is there a therapeutic role for IGF-1? / Moses, A.C. -- Insulin-like growth factors in the treatment of neurological disease / Leinninger, G.M., Feldman, E.L. -- Insulin-like growth factor system in amyotrophic lateral sclerosis / Wilczak, N., De Keyser, J
Summary The IGF system pervades the fields of development, linear and cellular growth and metabolism. Not only is the functional integrity of the IGF system crucial for normal linear growth and metabolism, it is also of fundamental importance for normal fetal development.This book consists of a compilation of chapters based on presentations at a symposium entitled 'IGFs and IGFBPs: Assessment and Therapeutic Benefit'. Highly qualified basic scientists and endocrinologists report new advances in the broad field of IGF physiology and pathophysiology, related to clinical medicine.New and topical areas of the IGF field are covered, focussing particularly on clinically relevant topics related to growth, pediatric and adult growth hormone deficiency, metabolic disorders, diabetes mellitus and neurology. Molecular and developmental defects are discussed, as are the contributions to clinical diagnosis and management of measurement of IGFs and IGFBPs. The therapeutic potential of recombinant human IGFs and IGFBPs in a range of disorders is also covered.The present volume of <i>Endocrine Development</i> will be of particular interest to scientists and clinicians working in IGF and IGF-related fields and to clinicians working in both pediatric and adult endocrinology and metabolism
Bibliography Includes bibliographical references and index
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Print version record
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
Subject Somatomedin.
Insulin-like growth factor-binding proteins.
Insulin-Like Growth Factor Binding Proteins -- physiology
Insulin-Like Growth Factor Binding Proteins -- genetics
Insulin-Like Growth Factor Binding Proteins -- therapeutic use
Insulin-Like Growth Factor Binding Proteins
MEDICAL -- Biochemistry.
Insulin-like growth factor-binding proteins.
Insulin-like Growth Factor I
Form Electronic book
Author Cianfarani, Stefano.
Clemmons, D. R.
Savage, M. O. (Martin O.)
ISBN 1423796748