| Description |
1 online resource (612 pages) |
| Contents |
Intro -- Handbook on Nanobiomaterials For Therapeutics and Diagnostic Applications -- Copyright -- Contents -- Contributors -- Chapter 1 Nanosomes for drug delivery -- 1.1 Introduction -- 1.2 Drug delivery system -- 1.3 Pharmacokinetics and pharmacodynamics -- 1.4 Types of nanosomes in drug delivery -- 1.4.1 Endosomes in drug delivery -- 1.4.2 Exosomes in drug delivery -- 1.4.3 Liposomes in drug delivery -- 1.4.4 siRNA-encapsulated nanosomes in drug delivery -- 1.4.4.1 Epidemiology -- 1.5 Nanosomes and gene therapy -- 1.6 Nanosome transportation mechanisms |
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1.7 Blockades of nanosome trafficking -- 1.8 Drug release -- 1.9 Conclusion -- References -- Chapter 2 Nanomaterials for bioimaging studies -- 2.1 Introduction -- 2.2 Dye-loaded fluorescent silica nanoparticles (SiNPs) in bioimaging -- 2.2.1 Properties of SiNPs -- 2.2.2 Synthesis of SiNPs -- 2.2.3 Bioimaging -- 2.2.3.1 Typical fluorescent dye-doped SiNPs -- 2.2.3.2 Near-infrared fluorescent dye-doped SiNPs -- 2.2.3.3 Two-photon fluorescent dye silica nanoparticles -- 2.3 Imaging, targeting, and drug delivery using multifunctional inorganic nanoparticles (MiNPs) |
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2.4 Lanthanide-doped upconverting nanoparticles -- 2.4.1 The fundamental mechanism of UCNPs -- 2.4.2 Synthesis of UCNPs -- 2.4.3 UCNPs as image contrasting agents -- 2.5 Conclusions -- References -- Chapter 3 Exosome RNAs as biomarkers for cancer therapy -- 3.1 Introduction -- 3.2 Exosomes in cancer -- 3.3 Exosomes from body fluids -- 3.3.1 Resistance to cancer therapeutics -- 3.3.2 Nanodiagnostic exosomes by electrochemical biosensing -- 3.3.3 Characterization of salivary exosomes -- 3.4 Exosomes derived from tumor cells -- 3.4.1 Role of exosomes in metastasis of cancer cells |
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3.4.2 State of exosomes within the enlargement of cancer tissue amidst angiogenesis -- 3.5 Exosomes-Role in maintaining a strategic distance from an assault from immune cells -- 3.6 Potential benefits of exosomal RNAs in malignant growth diagnostics and treatment -- 3.6.1 Exosomal ncRNAs as malignancy indicative biomarkers -- 3.6.2 Uses of exosomal noncoding RNAs (ncRNAs) as cancer therapeutics -- 3.7 Conclusion -- References -- Chapter 4 Tumoral delivery of nanotherapeutics -- 4.1 Introduction -- 4.2 Therapeutics employed for tumor treatment -- 4.2.1 Chemotherapy -- 4.2.2 Genetic material |
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4.2.3 Photodynamic therapy (PDT) -- 4.2.4 Photothermal therapy (PTT) -- 4.2.5 Immunotherapy -- 4.2.6 Sonodynamic therapy -- 4.3 Barriers to tumoral delivery of nanotherapeutics -- 4.3.1 Barriers in the systemic circulation -- 4.3.2 Barriers in the tumor microenvironment -- 4.3.3 Barriers at cellular level -- 4.3.4 Heterogeneity in vascular density among different tumors -- 4.4 Potential of nanocarriers for tumoral delivery of therapeutics -- 4.4.1 Chemotherapy -- 4.4.2 Gene therapy -- 4.4.3 PDT -- 4.4.4 PTT -- 4.4.5 Combination therapy -- 4.4.6 Targeted therapy -- 4.4.6.1 Passive targeting |
| Notes |
4.4.6.2 Active targeting |
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Includes index |
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Print version record |
| Subject |
Biomedical materials.
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Nanostructured materials.
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Nanobiotechnology.
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Nanostructures
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Biomedical materials
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Nanobiotechnology
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Nanostructured materials
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| Genre/Form |
handbooks.
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Handbooks and manuals
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Handbooks and manuals.
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Guides et manuels.
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| Form |
Electronic book
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| Author |
Anand, Krishnan
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Saravanan, Muthupandian, 1977-
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Chandrasekaran, Balakumar
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Kanchi, Suvardhan.
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Panchu, Sarojini Jeeva
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Chen, Quan-Sheng
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| ISBN |
9780128219140 |
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0128219149 |
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