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E-book
Author Budisa, Nedijko, Dr

Title Engineering the genetic code : expanding the amino acid repertoire for the design of novel proteins / Nediljko Budisa
Published Weinheim : Wiley-VCH Verlag GmbH & Co. KGaA, 2006
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Description 1 online resource (pages)
Contents Engineering the Genetic Code; Foreword; Contents; Preface; 1 Introduction; 2 A Brief History of an Expanded Amino Acid Repertoire; 3 Basic Features of the Cellular Translation Apparatus; 4 Amino Acids and Codons -- Code Organization and Protein Structure; 5 Reprograming the Cellular Translation Machinery; 6 Implications and Insights: From Reprogrammed Translation and Code Evolution to Artificial Life; 7 Some Practical Potentials of Reprogrammed Cellular Translation; Epilogue; Index
Summary The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique. Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given. Essential reading for all molecular life scientists
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Protein Engineering.
Amino Acids.
Amino acids -- Synthesis.
Protein engineering.
Proteins -- Biotechnology.
Form Electronic book
Author John Wiley & Sons.
ISBN 1280854170
3527312439 (print edition)
3527607099 (electronic bk.)
3527607188 (electronic bk.)
9781280854170
9783527312436 (print edition)
9783527607099 (electronic bk.)
9783527607181 (electronic bk.)