Description |
1 online resource (pages) |
Contents |
Engineering the Genetic Code; Foreword; Contents; Preface; 1 Introduction; 2 A Brief History of an Expanded Amino Acid Repertoire; 3 Basic Features of the Cellular Translation Apparatus; 4 Amino Acids and Codons -- Code Organization and Protein Structure; 5 Reprograming the Cellular Translation Machinery; 6 Implications and Insights: From Reprogrammed Translation and Code Evolution to Artificial Life; 7 Some Practical Potentials of Reprogrammed Cellular Translation; Epilogue; Index |
Summary |
The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique. Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given. Essential reading for all molecular life scientists |
Bibliography |
Includes bibliographical references and index |
Notes |
Print version record |
Subject |
Protein Engineering.
|
|
Amino Acids.
|
|
Amino acids -- Synthesis.
|
|
Protein engineering.
|
|
Proteins -- Biotechnology.
|
Form |
Electronic book
|
Author |
John Wiley & Sons.
|
ISBN |
1280854170 |
|
3527312439 (print edition) |
|
3527607099 (electronic bk.) |
|
3527607188 (electronic bk.) |
|
9781280854170 |
|
9783527312436 (print edition) |
|
9783527607099 (electronic bk.) |
|
9783527607181 (electronic bk.) |
|