| Description |
1 online resource (444 pages) |
| Series |
Translational Epigenetics Ser. ; v. Volume 8 |
|
Translational Epigenetics Ser
|
| Contents |
Front Cover; EPIGENETICS OF CANCER PREVENTION; Translational Epigenetics Series; EPIGENETICS OF CANCER PREVENTION; Copyright; Contents; Contributors; Foreword; I -- MOLECULAR EPIGENETIC TARGETS OF NATURAL PRODUCTS; 1 -- Genetic and Epigenetic Targets of Natural Dietary Compounds as Anticancer Agents; INTRODUCTION; GENETIC MUTATIONS IN CANCER TARGETED BY NATURAL DIETARY PRODUCTS; Epidermal Growth Factor Receptor; p53; K-Ras; MECHANISMS OF EPIGENETIC MODIFICATIONS; DNA Methylation; Histone Modification; Noncoding RNAs; EPIGENETIC TARGETS MODIFIED BY NATURAL DIETARY PRODUCTS AGAINST CANCER; DNMT |
|
HDACHAT; miRNA; CONCLUSION; References; 2 -- Epigenetic Dietary Interventions for Prevention of Cancer; INTRODUCTION; EPIGENETIC REGULATION OF GENE ACTIVITY; Altered DNA Methylation and Abnormal Gene Expression; DNA Methyltransferases and Demethylases During Cancer Progression; Histone Modification; Histone Acetyltransferases and Deacetylases; Histone Methyltransferases and Demethylases; EPIGENETIC THERAPY OF CANCER; CANCER AND LIFESTYLE RISK FACTORS; EPIGENETIC ACTIONS OF DIETARY PHYTOCHEMICALS; DNA Methylation and Dietary Modulators |
|
Role of Methyl Donors and Nutrients of One-Carbon Metabolism in DNA MethylationPolyphenols Possessing the Catechol Group; Soy Isoflavones and Phytoestrogens; Parthenolide and Curcumin; Selenium and Zinc; Sulforaphane; Retinoic Acid; Plant-Derived Natural Compound and Histone Modifications; Dietary Fiber (Butyrate); Cambinol and Dihydrocoumarin; Isothiocyanates; Anacardic Acid; Allyl Compounds; Polyphenols; Selenium; CONCLUSIONS; Acknowledgments; References; 3 -- Natural Anticancer Agents: Modifying the Epigenome to Prevent and Treat Cancer; INTRODUCTION: EPIGENETICS AND CANCER PREVENTION |
|
EPIGENETIC MECHANISMS FOR CANCER INTERVENTIONRole of DNA Methylation; Role of DNA Histone Modification; Role of Noncoding RNAs; EPIGENETICALLY SENSITIVE CANCERS AND TARGETS FOR INTERVENTIONS; NATURAL PRODUCTS: SOURCE OF EPIGENETIC MODIFIERS; Polyphenolic Compounds; Apigenin; Curcumin; Epigallocatechin Gallate; Genistein; Quercetin; Kaempferol; Luteolin; Resveratrol; Sulfur-Containing Compounds; Diallyl Disulfide and DIM; Isoquinoline Alkaloids and Isothiocyanates; Berberine; Sulforaphane; Other Compounds of Natural Origin With Epigenetic Properties |
|
MODEL SYSTEMS: PRECLINICAL EVALUATION OF POTENTIAL EPIGENETIC MODIFIERS FROM NATURENATURAL EPIGENETIC COMPOUNDS AS ADJUVANTS FOR CANCER THERAPY; CONCLUSIONS AND FUTURE RESEARCH DIRECTIONS; References; Further Reading; 4 -- Histone Deacetylase Inhibitors in Cancer Prevention and Therapy; INTRODUCTION; Genome Organization; Regulation of Gene Expression; ACETYLATION OF HISTONE AND NONHISTONE PROTEINS REGULATES THEIR FUNCTIONS; Histones; Nonhistone Proteins; HISTONE DEACETYLASE COMPLEXES ARE RESPONSIBLE FOR THE DEACETYLATION OF HISTONES AND NONHISTONE PROTEINS |
| Notes |
HISTONE DEACETYLASE COMPLEXES REGULATE MANY CELLULAR PROCESSES |
|
Print version record |
| Subject |
Epigenetics.
|
|
Cancer -- Prevention.
|
|
Cancer -- Prevention
|
|
Epigenetics
|
| Form |
Electronic book
|
| Author |
Bhatia, Deepak
|
| ISBN |
9780128125663 |
|
0128125667 |
|
