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Book Cover
E-book
Author Spencer, John

Title Microwaves in Drug Discovery and Development
Published London : Future Science Group, 2014

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Description 1 online resource (214 pages)
Series Microwaves in Drug Discovery and Development : Recent Advances, 2047-332X
Contents Microwaves in drug discovery and development: recent advances -- Microwave-assisted processing techniques in medicinal chemistry -- Microwave-assisted medicinal chemistry: examples from a pharmaceutical company -- Microwave-assisted synthesis of anti-tuberculosis, HIVĂ‚ and hepatitis C agents -- Synthesis of drug-like molecules for respiratory diseases: utilizing microwave chemistry -- Microwave-assisted synthesis of MK2 inhibitors for targeting p38 MAPK signal transduction in Werner syndrome cells -- Microwave-assisted organic chemistry: monitoring reactions
Microwave-assisted synthesis of sulfonamidesMicrowave-assisted synthesis of natural products (analogs) with potential biological applications -- Arylboronate coupling partners: towards the synthesis of biaryl derivatives -- Development of nucleoside analogues under microwave irradiation -- Classical and microwave-assisted synthesis of cucurbit[n]urils, hemicucurbit[n]urils and bambus[n]urils -- Microwave applications in pharmaceutical dosage form development -- _GoBack -- _GoBack -- _GoBack -- _GoBack -- _GoBack -- _GoBack -- _GoBack -- _GoBack
Summary There can be little doubt that the introduction of proprietary instrumentation for microwave-assisted synthesis has made a dramatic impact on drug discovery. The uptake of this technology in the field has been rapid and universal, although there remains a number of key challenges, such as difficulties with reaction monitoring, facility for scale-up, and integration with other emerging technologies, as well as key ongoing debates, including the presence (or indeed absence) of specific microwave effects. This book brings together a series of excellent reviews from world-leading groups in the fie
Bibliography Includes bibliographical references
Notes Print version record
Subject Drugs -- Analysis.
Drugs -- Analysis
Form Electronic book
Author Bagley, Mark
ISBN 9781910419304
1910419303