| Description |
1 online resource |
| Contents |
Intro -- Zika Virus Impact, Diagnosis, Control, and Models -- Copyright -- Dedication -- Contents -- Contributors -- Foreword -- Preface -- Section A: Zika virus: Setting the scene -- Chapter 1: How Zika virus emerged and spread worldwide -- African origin of Zika virus and its dispersion to Asia -- Introduction of ZIKV in Oceania -- Introduction of ZIKV in the Americas -- Reintroduction of ZIKV in Africa -- Policy and procedures -- Mini-dictionary of terms -- Key facts -- Summary points -- References -- Chapter 2: Clinical neurological spectrum of adult and congenital ZIKV infection: An overview of virology, pathogenesis, ... -- Virology of Zika virus -- Introduction to Zika virus -- Epidemiology of Zika virus -- Pathogenesis of Zika virus -- Mechanisms of infection -- Infection via mosquitoes -- Horizontal transmission within humans -- Vertical transmission and mechanisms of entry into the nervous system -- Cross-reactivity and cross-protection between ZIKV and DENV infections -- Clinical presentation of ZIKV infection -- Neurological manifestations of ZIKV infection -- ZIKV-associated Guillain-Barré syndrome -- ZIKV-associated central nervous system involvement -- Congenital ZIKA syndrome -- Ophthalmic manifestations of ZIKV -- Clinical management of ZIKA infections -- Diagnosis of ZIKA infections -- Follow-up in pregnant women -- Treatment of ZIKV infections -- Possibility of a vaccine for ZIKA? -- Subsection policy and procedures -- Screening for ZIKA virus among pregnant women -- Screening for congenital microcephaly -- Mini-dictionary of terms -- Key facts of Zika virus neurological manifestations -- Key facts of congenital ZIKV syndrome -- Summary points -- References -- Chapter 3: Classification of Zika virus sequences with respect to their species and subspecies -- Introduction -- Zika virus sequences from African countries |
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Zika virus sequences from the Asian region -- Evolution of the Asian lineage -- Spread of the Asian lineage to Pacific and Americas -- The proposition of three lineages -- Conclusion -- Policy and procedures -- Sequencing -- Classification of sequences -- Genetic sequence database -- Mini-dictionary of terms -- Key facts of Zika virus lineage -- Summary points -- References -- Chapter 4: Health knowledge about Zika virus: Brazil aspects -- Introduction -- Public health response on vector control: Communicational strategies and perceptions of risk -- Advice to delay pregnancy as a public health strategy -- Awareness and knowledge about Zika virus in Brazil -- Consequences of the Zika virus epidemics on health services response and on reproductive behaviors -- Conclusion -- Policy and procedures -- Mini-dictionary of terms -- Key facts of Zika virus knowledge in Brazil -- Summary points -- References -- Chapter 5: Zika virus infection and replication organelle biogenesis -- Introduction -- Zika virus infection induces intracellular membrane remodeling and viral replication organelle formation -- Viral proteins required for viral replication organelle biogenesis -- ER membrane proteins involved in the formation of viral replication organelle -- Endosomal sorting complex required for transport-mediated membrane invagination and fission -- Autophagic machinery is activated in the ZIKV-infected cells -- Membrane lipids involved in the formation of viral replication organelle -- Concluding remarks -- Policy and procedures -- Mini-dictionary of terms -- Key facts of virus replication organelle biogenesis -- Summary points -- References -- Section B: Microcephaly and congenital syndromes -- Chapter 6: Microcephaly: Zika and other congenital infections -- Microcephaly and TORCH agents -- Development of microcephaly in congenital infections |
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Pathogen characteristics -- Zika virus -- Rubella virus -- Toxoplasma gondii -- Cytomegalovirus -- The pathogenesis of congenital infections -- Zika virus -- Rubella virus -- Toxoplasma gondii -- Cytomegalovirus -- Policy and procedures -- Mini-dictionary of terms -- Key facts on microcephaly secondary to intrauterine infections -- Summary points -- References -- Chapter 7: Zika and impact on the nervous system in children -- Introduction -- Epidemiology -- Clinical manifestations -- Congenital Zika virus infection -- Neurological complications associated with Zika infection -- Neuropathogenesis -- Diagnosis -- Management -- Prevention -- Mini-dictionary of terms -- Key facts -- Summary points -- References -- Chapter 8: Use of induced pluripotent stem cells and cerebral organoids to profile Zika virus infection: Features and fin ... -- Introduction -- Experimental models to study neurological diseases -- Induced pluripotent stem cells -- iPSCs X Zika virus -- Cerebral organoids -- Cerebral organoids X Zika virus -- Perspectives and conclusions -- Policy and procedures -- Materials and methods -- Mini-dictionary of terms -- Key facts -- Summary points -- References -- Chapter 9: Zika, miRNAs, and microcephaly genes -- Introduction -- ZIKV-induced cranial morphology -- Molecular pathogenesis -- Microcephaly genes -- ZIKV and miRNAs -- Microcephaly genes -- MCPH genes and the miRs connection -- MCPH mutations and the miR link -- Summary points -- References -- Further reading -- Chapter 10: Adherens junctions and cell polarity: What they are and how they relate to congenital Zika virus syndrome -- Cadherin-based adherens junctions and neural development -- Cell polarity and symmetric versus asymmetric cell division -- Flaviviruses and their impact on the expression and distribution of cell adhesion molecules |
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Current knowledge on the impact of N-cadherin-based AJs and apical-basal polarity of RGCs in ZIKV-induced neuropathology -- Policy and procedures -- Mini-dictionary of terms -- Key facts of neurodevelopmental disorders -- Summary points -- References -- Section C: Guillain-Barré syndrome -- Chapter 11: Severe Guillain-Barré syndrome -- Introduction -- Pathophysiology of Guillain-Barré syndrome -- Clinical presentation -- Severe GBS -- Laboratory tests -- Cerebrospinal fluid analysis -- Electrodiagnostic studies -- Antiganglioside antibodies and preceding infections -- Imaging -- Treatment -- IVIG -- Plasma exchange -- Combination treatment options -- Zipper method -- Policy and procedures: Diagnosis and treatment of Guillain-Barré syndrome -- Treatment -- Mini-dictionary of terms -- Key facts of plasma exchange -- Summary points -- References -- Chapter 12: Oxidative stress in Guillain-Barré syndrome and linkage with neurology -- Introduction -- Oxidative stress in demyelinating diseases -- Free radicals and enzymatic antioxidation in GBS -- GBS and lipophilic antioxidants -- Uric acid, albumin, and haptoglobin as the antioxidant substrate in patients with GBS -- T cell activity in GBS -- Policy and procedures -- Mini-dictionary of terms -- Key facts of oxidative stress in GBS -- Summary points -- References -- Chapter 13: Neuromuscular effects and rehabilitation in Guillain-Barré syndrome -- Introduction -- Pharmacological treatment -- Multidisciplinary rehabilitation -- Exercise -- Neuromuscular electrical stimulation -- Virtual motor rehabilitation system -- Safety -- Policy and procedures -- Neuromuscular electrical stimulation protocol -- Mini-dictionary of terms -- Key facts of neuromuscular rehabilitation in GBS -- Summary points of neuromuscular rehabilitation in GBS -- References |
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Chapter 14: Postinfectious demyelinating diseases: Guillain-Barré syndrome and beyond -- Introduction -- Zika virus and peripheral nervous system inflammatory and demyelinating diseases -- Zika virus and central nervous system inflammatory and demyelinating diseases -- Challenges in the diagnosis of ZIKV and the role of other flavivirus infection -- Conclusions -- Policy and procedures -- International classification criteria for inflammatory demyelinating diseases of the central and peripheral nervous system -- Zika antibody and nucleic acid amplification testing -- References (related to policy and procedures) -- Mini-dictionary of terms -- Key facts -- Key facts of Zika virus-related neurological disorders -- Key facts of demyelinating diseases -- Summary points -- References -- Chapter 15: Linking in placental alterations, Zika virus, and Guillain-Barré syndrome -- Introduction -- The placenta and vertical transmission -- Placental permissiveness to ZIKV -- Histopathological aspects and changes in ZIKV-infected placentas -- Cell subpopulations and cytokines in ZIKV-infected placentas -- The Guillain-Barré syndrome -- The clinical of GBS -- The GBS associated with ZIKV infection -- Conclusion -- Policy and procedures -- Mini-dictionary of terms -- Key facts of ZIKV-infected placentas and GBS associated to ZIKV -- Summary points -- References -- Section D: Case studies and short reports -- Chapter 16: Case study: Neuroimaging of adults and Zika virus -- Introduction -- Case study -- Acute disseminated encephalomyelitis -- Imaging findings of acute disseminated encephalomyelitis -- Acute disseminated encephalomyelitis and Zika virus -- Conclusion -- Policy and procedures -- Mini-dictionary of terms -- Key facts of Zika virus infection complicated by acute disseminated encephalomyelitis -- Summary points -- References |
| Subject |
Zika virus.
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Guillain-Barré syndrome.
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Neurosciences.
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Zika Virus
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Neurosciences
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Guillain-Barre Syndrome
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Guillain-Barré syndrome
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Neurosciences
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Zika virus
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| Form |
Electronic book
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| Author |
Martin, Colin R., 1964-
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Hollins Martin, Caroline.
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Preedy, Victor R.
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Rajendram, Rajkumar.
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| ISBN |
9780323903097 |
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0323903096 |
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