| Description |
1 online resource |
| Contents |
880-01 Introduction and Scientific Principles. From Hemoglobin Based Oxygen Carrier to Oxygen Therapeutics, Blood Substitutes, Nanomedicine and Artificial Cells / Thomas Ming Swi Chang -- From the Atmosphere to the Mitochondrion: The Oxygen Cascade / George P. Biro -- Biochemistry of Hemoglobin / Andrea Mozzarelli, Stefano Bruno, Luca Ronda -- The Role of Blood and Plasma Viscosity in Restoring Oxygen Delivery Capacity / Amy G. Tsai, Judith Martini, Beatriz Y. Salazar Vázquez, Pedro Cabrales [and others] -- Hemorrhagic Shock and Current Treatments. Pathophysiology of Hemorrhagic Shock and Resuscitation / Fredric M. Pieracci, Walter L. Biffl -- Allogeneic Blood Transfusion for Surgical and Traumatic Hemorrhage / Mercy Kuriyan, Jeffrey L. Carson -- Pre-Hospital Fluid Resuscitation in Civilian and Military Populations / Robert M. Van Haren, Chad M. Thorson, Col Lorne H. Blackbourne, Kenneth G. Proctor |
|
880-01/(S 39. International Consortium for Development of Hemoglobin-Based Oxygen Carriers, Oxygen Therapeutics and Multifunctional Resuscitation Fluids-A White Paper / Hiromi Sakai -- pt. I Fractional Dynamics and Nonlinearity -- 1. Nonlinear Self-Adjointness for some Generalized KdV Equations / M. Rosa -- 2. Weak Self-Adjointness and Conservation Laws for a Family of Benjamin-Bona-Mahony-Burgers Equations / M.S. Bruzon -- 3. Some Analytical Techniques in Fractional Calculus: Realities and Challenges / Jun-Sheng Duan -- 4. Application of the Local Fractional Fourier Series to Fractal Signals / J.A. Tenreiro Machado -- 5. Parameter Optimization of Fractional Order PIλ Dμ Controller Using Response Surface Methodology / Aslan Deniz Karaoglan -- 6. Dynamical Response of a Van der Pol System with an External Harmonic Excitation and Fractional Derivative / Grzegorz Litak |
|
Current Issues of HBOCs and Regulatory Framework. NIH/FDA/DOD Interagency Working Group on Oxygen Therapeutics / Phyllis Mitchell, Richard Weiskopf, Warren M. Zapol -- Regulatory Framework for Hemoglobin-Based Oxygen Carrier Trials / Basil Golding -- Approaches to HBOCs. HBOCs from Chemical Modification of Hb / Ronald Kluger, Francine E. Lui -- Design of Nonhypertensive Conjugated Hemoglobins as Novel Resuscitation Fluids / Seetharama A. Acharya, Marcos Intaglietta, Amy G. Tsai, Fantao Meng -- Cellular-Type Hemoglobin-Based Oxygen Carriers to Mimic the Red Blood Cell Structure / Hiromi Sakai -- Recombinant Octameric Hemoglobins as Resuscitation Fluids in a Murine Model of Traumatic Brain Injury Plus Hemorrhagic Shock / Xianren Wu, Nancy T. Ho, Tong-Jian Shen, Vincent Vagni, David K. Shellington [and others] |
|
Liposome-Encapsulated Hemoglobin as an Artificial Oxygen Carrier: Technological Features, Manufacturing and Issues for Practical Application / Shinichi Kaneda, Takanobu Ishizuka, Hiroshi Goto, Hiroaki Kasukawa -- Zero-Link Hemoglobin (OxyVita®): Impact of Molecular Design Characteristics on Pre-clinical Studies / John P. Harrington, Hanna Wollocko -- Polynitroxylated Pegylated Hemoglobin (PNPH): A Nanomedicine for Critical Care and Transfusion / Li Ma, Frances M. Thompson, Dong Wang, Carleton J.C. Hsia -- ATP-Adenosine-GSH Crosslinked Hb, An Oxygen Carrier with Pharmacological Properties for Multiple Therapeutic Indications / Jan Simoni, Grace Simoni, John F. Moeller -- Albumin-Heme Oxygen Carriers / Teruyuki Komatsu -- Recombinant Human Hb-SOD Fusion Proteins / Marie Grey, Khuanpiroon Ratanasopa, Leif Bülow -- In-Vitro Production of Functional RBCs from Hematopoietic Stem Cells / Eun Jung Baek, Hyun Ok Kim -- Potential Applications of HBOCs |
|
Liposome-Encapsulated Hemoglobin: Potential Clinical Applications / Akira T. Kawaguchi, Chieko Murayama, Fumiaki Yoshiba, Hiroyuki Furuya, Mariko Yamano [and others] -- Biocompatibility of Hemoglobin Vesicles, a Cellular-Type Artificial Oxygen Carrier, on Blood Cells and Plasma Proteins In Vitro and In Vivo / Hiroshi Azuma, Mitsuhiro Fujihara, Hiromi Sakai -- Polymerized Human Placenta Hemoglobin: Organ Protective Effects and Alternative Clinical Uses / Tao Li, Chengmin Yang, Jin Liu, Jiaxin Liu, Wang Hong -- Low Volume Resuscitation with HBOCs in Hemorrhagic Shock / P.S. Reynolds, R.W. Barbee, K.R. Ward -- Ischemic Rescue with Hemoglobin-Based Oxygen Carriers / Raymond C. Koehler -- Preclinical Evaluations of HBOCs. Pre-clinical Evaluation of Hemoglobin Based Oxygen Carriers: Animal Models and Biomarkers / Paul W. Buehler, Felice D'Agnillo |
|
The Hemoglobin-Based Oxygen Carrier, HBOC-201, as a Resuscitation Fluid for Traumatic Hemorrhagic Shock: The Naval Medical Research Center Experience / Charles Auker, Paula Moon-Massat, Anke Scultetus, Richard McCarron, Daniel Freilich -- Cellular-Type Hemoglobin-Based Oxygen Carrier as a Resuscitative Fluid for Hemorrhagic Shock: Acute and Long-Term Safety Evaluation Using Beagle Dogs / Tatsuhiko Ikeda, Hirohisa Horinouchi, Yoraro Izumi, Hiromi Sakai, Koichi Kobayashi -- HBOC Clinical Trials. Key Adverse Events in Recent HBOC Phase III Clinical Trials and Their Causal Relationship to Test HBOC's / Colin F. Mackenzie -- Some Critical Comments on the Major HBOC Clinical Trials / George P. Biro -- Compassionate Use Cases Treated with Hemoglobin-Based Oxygen Carriers / Paula Moon-Massat, Daniel Freilich -- HBOC-Mediated Adverse Effects. Acellular Hemoglobin-Based Oxygen Carrier Mediated Blood Pressure Elevation and Vasoconstriction: A Review of Proposed Mechanisms and Contributing Factors / Hae Won Kim |
|
HBOCs and Cardiac Integrity / T.N. Estep -- Effects of Hemoglobin-Based Oxygen Carriers on Blood Coagulation / Jonathan S. Jahr, Molly Chung, Afsaneh Anvarhosseini, Hae Won Kim -- Redox Activity of Cell-Free Hemoglobin: Implications for Vascular Oxidative Stress and Endothelial Dysfunction / Felice D'Agnillo -- HBOC Interferences with Routine Clinical Laboratory Tests / Younes Smani -- Vasoconstriction, Hypertension and Oxidative Toxicity are Regulated by Polymerized Hemoglobin Size / Brian M. Belcik, Andre F. Palmer -- Acellular Hemoglobin-Based Oxygen Carrier Induced Vasoactivity: A Brief Review of Potential Pharmacologic Remedies / Hae Won Kim, Chi-Ming Hai, A. Gerson Greenburg -- A Call for Collaborative Research and Development. International Consortium for Development of Hemoglobin-Based Oxygen Carriers, Oxygen Therapeutics and Multifunctional Resuscitation Fluids-A White Paper / Hae Won Kim, Jonathan S. Jahr, Andrea Mozzarelli, Hiromi Sakai |
| Summary |
Hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will provide readers a comprehensive review of topics involved in the HBOC development. It focusses on current products and clinical applications as well as on emerging technologies and future prospects |
| Notes |
Title from PDF title page (viewed on February 18, 2014) |
| Bibliography |
Includes bibliographical references |
| In |
Springer eBooks |
| Subject |
Oxygen -- Physiological transport.
|
|
Oxygen therapy.
|
|
Blood substitutes.
|
|
Hemoglobin.
|
|
Hemoglobins
|
|
Blood Substitutes
|
|
Oxygen -- therapeutic use
|
|
Oxygen Inhalation Therapy
|
|
hemoglobin.
|
|
MEDICAL -- Pharmacology.
|
|
Chimie.
|
|
Science des matériaux.
|
|
Hemoglobin
|
|
Blood substitutes
|
|
Oxygen -- Physiological transport
|
|
Oxygen therapy
|
| Form |
Electronic book
|
| Author |
Kim, Hae-wŏn, editor.
|
|
Greenburg, A. Gerson, editor.
|
| ISBN |
9783642407178 |
|
364240717X |
|
3642407161 |
|
9783642407161 |
|
