| Description |
1 online resource (376 pages) |
| Series |
Current Clinical Neurology |
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Current clinical neurology.
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| Contents |
Series Editor Introduction; Contents; Contributors; Part I: General Section; 1: Status Epilepticus -- Lessons and Challenges from Animal Models; Introduction; History and Definition of SE; Epidemiology; Etiology; Animal Models of SE; Electrical Stimulation Models; Chemical Models of SE: Pilocarpine and Lithium-Pilocarpine; Studies of the Transition from Single Seizures to SE: GABAAR; Studies of the Transition from Single Seizures to SE: NMDAR; Chemical Models of SE: Kainic Acid; Chemical Models of SE: Nerve Agents; In Vitro Models Used to Study Basic Physiology of SE; Brain Slices |
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4-Aminopyridine ModelLow Magnesium Model; High Potassium Model; Organotypic Slice Culture Model; Other Techniques; Intrinsic Optical Imaging; Dissociated Cultures; Pathophysiological Changes During SE; Lessons from Animal Models of SE; SE Is Maintained by an Underlying Change in Limbic Circuit Excitability That Does Not Depend on Continuous Seizure Activity; The Initiation and Maintenance Phases of SE Are Pharmacologically Distinct; Initiation Is Accompanied by a Loss of GABA Inhibition; Maintenance of SSSE Depends on the Activation of NMDA Receptors |
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Time-Dependent Development of Pharmacoresistance Maladaptive Seizure-Induced Receptor Trafficking Plays a Role in the Development of Pharmacoresistance; Potentiation of NMDA Synaptic Responses May Play a Role in Maintaining SE; Therapeutic Implications of Seizure-Associated Receptor Trafficking; The Case for Polytherapy; If Treatment Is Delayed, Triple Therapy May Be Needed; Timing of Polytherapy Is Critical; The Earlier the Better; Issues Commonly Encountered in Translational Research; Conclusions; References; 2: Impact of Seizures on Outcome; Introduction |
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Continuous Electroencephalogram Monitoring Terminology; Literature Search Methods; Electrographic Seizures in the Intensive Care Unit; Outcome in Sepsis; Outcome in Traumatic Brain Injury; Outcome in Subarachnoid Hemorrhage; Outcome in Stroke; Outcome After Cardiac Surgery; Outcome After Cardiac Arrest; Outcome in Tumors; Pediatric Outcome; Conclusions; References; 3: Diagnosing and Monitoring Seizures in the ICU: The Role of Continuous EEG for Detection and Management of Seizures in Critically Ill Patients, Including the Ictal-Interictal Continuum; Introduction; How to Monitor |
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Data Analysis Who to Monitor; EEG Patterns Encountered During EEG Monitoring; How Long to Monitor; Cost-Effectiveness; Future Directions; Summary; References; 4: Seizures and Quantitative EEG; Introduction; Overview of Quantitative EEG Methods; Amplitude-Based Methods; Displays Derived from Spectrograms; Methods for Monitoring Burst Suppression; Automated Seizure Detection; Automated Detection of Other Epileptiform Patterns; Fundamentals of Spectrograms; Motivation for Spectral Analysis; Spectral Decomposition: Fourier Transforms and the "FFT." |
| Summary |
Updated and expanded to provide the neurologic, intensive and critical care communities a comprehensive guide to common critical care illnesses and seizures, this third edition remains the premier resource on seizures in critical care. In addition to covering etiology, pathophysiology, diagnosis, differential diagnosis and treatment options, chapters feature the latest technologies and treatments and integrate current literature. This unique and specialized text offers neurologists, intensivists, neurosurgeons, trauma surgeons, epileptologists, electrophysiologists and residents in various specialties clarity on this challenging set of comorbidities |
| Notes |
Signal Sharpening Manifests as Amplitude Spectrum Broadening |
| Bibliography |
Includes bibliographical references at the end of each chapters and index |
| Notes |
Print version record |
| Subject |
Medicine.
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Emergency medicine.
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Neurology.
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Nervous system -- Surgery.
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Medicine
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Emergency Medicine
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Neurology
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Neurosurgical Procedures
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Neurosurgery
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medicines (material)
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medicine (discipline)
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Emergency medicine
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Medicine
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Nervous system -- Surgery
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Neurology
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| Form |
Electronic book
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| Author |
Claassen, Jan
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| ISBN |
9783319495576 |
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3319495577 |
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9783319495552 |
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3319495550 |
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