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Book Cover
E-book

Title Rosacea / John Havens Cary, Howard I. Maibach, editors
Published Cham, Switzerland : Springer, [2020]

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Description 1 online resource
Series Updates in clinical dermatology
Updates in clinical dermatology.
Contents Intro -- Preface -- Contents -- Contributors -- 1: Introduction to Clinical Rosacea -- Rosacea Is a Syndrome and Not a Pathogenically Defined Disease -- History of Classification of Rosacea: Distinction from Acne and Recognition of Phenotypic Subtypes -- The Four Classic Phenotypic Subtypes of Rosacea Have Important Utilities -- The Flawed Proposal to Eliminate the Classic Phenotypic Subtypes -- The Classic Phenotypic Subtypes Are Useful and Will Persist -- Incidence -- History -- History of Present Illness -- Past Medical History -- Medication History -- Family History -- Social History
Review of Systems -- Physical Exam -- Differential Diagnoses -- Histology -- References -- 2: Pathophysiology of Rosacea -- Introduction -- Current Concepts of the Pathophysiology -- Genes in Rosacea -- Innate Immunity and Adaptive Immunity -- Neuroimmune and Neurovascular Dysregulation -- Novel Insights and Promising Targets -- Future Studies -- Conclusion -- References -- 3: Genetics of Rosacea -- Background -- Epidemiology -- Familial Inheritance Studies -- Twin Concordance Studies -- Gene Association Case-Control Studies -- Molecular and Functional Data -- Endoplasmic Reticulum (ER) Stress
Toll-Like Receptor (TLR)-2 -- Antimicrobial Peptides -- Transient Receptor Potential Vanilloid 1 (TRPV1) -- Neurovascular Factors -- Mast Cells -- IL-17 -- TSLP -- Associations with Comorbidities -- Conclusion and Future Directions -- References -- 4: Evidence-Based Management -- Introduction -- Environmental Modification -- Topical Therapies -- Metronidazole -- Azelaic Acid -- Sodium Sulfacetamide-Sulfur -- Calcineurin Inhibitors -- Crotamiton, Ivermectin, and Permethrin -- Clindamycin -- Retinoids -- Systemic Therapies -- Doxycycline and Minocycline -- Macrolides -- Antihypertensives
Isotretinoin -- Conclusion -- References -- 5: Difference in Vasoconstrictors: Oxymetazoline Versus Brimonidine -- Introduction -- Vascular Anatomy -- Brimonidine -- Pharmacodynamics and Pharmacokinetics -- Administration and Interactions -- Indication and Clinical Management -- Efficacy -- Adverse Effects -- Oxymetazoline -- Pharmacodynamics and Pharmacokinetics -- Administration and Interactions -- Indication and Clinical Management -- Efficacy -- Adverse Effects -- Oxymetazoline Versus Brimonidine -- Conclusion -- References -- 6: Treatment of Ocular Rosacea -- Introduction
Conservative Therapy -- Topical Medical Therapy -- Systemic Therapy -- Procedural and Surgical Therapy -- Future Directions -- Conclusion -- References -- 7: Physical Modalities for the Treatment of Rosacea -- Introduction -- Light and Laser Applications for Vascular Lesions -- Pulsed Dye Laser (PDL) -- KTP Laser -- Long-Pulsed Nd:YAG Laser -- Intense Pulse Light (IPL) -- Summary: Therapy of Vascular Lesions -- Physical Therapeutic Options in the Treatment of Phymatous Rosacea Manifestations -- Dermashaving (Scalpel) -- Dermabrasion -- Electrosurgery (Fig. 7.1a-c) -- Laser Surgery (Fig. 7.2a, b)
Summary Of Therapeutic Options in Phymatous Lesions of Rosacea
Bibliography Includes bibliographical references and index
Notes Online resource; title from digital title page (viewed on November 02, 2020)
Subject Rosacea.
Rosacea
Genre/Form Electronic books
Form Electronic book
Author Cary, John Havens, editor
Maibach, Howard I., editor
ISBN 3030520978
9783030520977