| Description |
1 online resource |
| Contents |
Abbreviations; Chapter 1: Anatomy and Pathophysiology of Retinal Pigment Epithelial Detachment; 1.1 Introduction; 1.2 The Retinal Pigment Epithelium: Interface Between Blood and Photoreceptors; 1.3 Function of the RPE; 1.4 Mechanisms of Adherence Between RPE and Photoreceptors in Health and Disease; 1.4.1 Basic Mechanisms in Health; 1.4.2 Transepithelial Transport in Disease; 1.5 Causes Leading to RPE Detachment; 1.5.1 Changes in Bruch's Membrane and in Sub-pigment-ƯEpithelial Space; 1.5.2 Changes in Choroid and Choriocapillaris |
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1.6 The Effect of RPE Detachment: Mesenchymal Transdifferentiation of the RPE1.7 Summary; References; Chapter 2: Imaging in Retinal Pigment Epithelial Detachment; 2.1 Introduction; 2.2 Angiography; 2.2.1 Fluorescein Angiography; 2.2.2 Indocyanine Green Angiography; 2.2.3 Angiography Summary; 2.3 Spectral Domain Optical Coherence Tomography; 2.3.1 SD-OCT Summary; 2.4 OCT-Angiography; 2.4.1 OCTA Summary; 2.5 Autofluorescence; 2.5.1 Fundus Autofluorescence; 2.5.2 Near-Infrared Autofluorescence; 2.5.3 Autofluorescence Summary; 2.6 Spectral Reflectance Imaging; 2.6.1 Blue Reflectance |
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2.6.2 Green Reflectance2.6.3 Near-Infrared Reflectance; 2.6.4 Multi-Color Scanning Laser Imaging; 2.6.5 Spectral Reflectance Imaging Summary; 2.7 Summary; Chapter 3: Retinal Pigment Epithelial Detachment in Age-Related Macular Degeneration; 3.1 Introduction; 3.2 Epidemiology; 3.3 Pathogenesis; 3.4 Clinical Examination; 3.5 Imaging; 3.6 Drusenoid PED; 3.7 Serous PED; 3.8 Vascularized and Fibrovascular PED; 3.9 Natural Course; 3.10 Therapy; 3.11 Differential Diagnosis; 3.12 Summary; References; Chapter 4: Drusenoid Retinal Pigment Epithelial Detachment; 4.1 Introduction |
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4.2 Classification and Definition4.3 Epidemiology; 4.4 Pathogenesis; 4.5 Clinical Examination; 4.5.1 Stereoscopic Funduscopy; 4.6 Imaging; 4.6.1 Optical Coherence Tomography; 4.6.2 Fundus Autofluorescence Imaging; 4.6.3 Fluorescein Angiography; 4.6.4 Indocyanine Green Angiography; 4.7 Natural History; 4.8 Therapeutic Intervention; 4.9 Differential Diagnosis of Drusenoid PED; 4.10 Summary; References; Chapter 5: Retinal Pigment Epithelial Detachment in Retinal Angiomatous Proliferation; 5.1 Introduction; 5.2 Epidemiology; 5.3 Pathogenesis; 5.4 Clinical Examination; 5.5 Imaging |
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5.5.1 Fluorescein Angiography5.5.2 ICGA; 5.5.3 OCT; 5.6 Natural History; 5.7 Therapy; 5.8 Differential Diagnosis; 5.9 Summary; References; Chapter 6: Retinal Pigment Epithelial Detachment in Polypoidal Choroidal Vasculopathy; 6.1 Introduction; 6.1.1 Epidemiology; 6.1.2 Pathogenesis; 6.1.3 Histopathology; 6.1.4 Clinical Examination; 6.2 Imaging; 6.2.1 Imaging of PCV in ICGA; 6.2.2 Imaging of PCV in OCT; 6.3 Natural History; 6.4 Therapy; 6.4.1 Laser Treatment (Photocoagulation):; 6.4.2 PDT; 6.4.3 Anti-VEGF Treatment; 6.4.4 Combination Treatment (vPDT and anti-VEGF); 6.5 Differential Diagnosis |
| Summary |
This excellently illustrated book offers detailed guidance on the differential diagnosis and therapy of detachment of the retinal pigment epithelium (PED), a frequently seen feature in various diseases of the eye, including age-related macular degeneration and its subtypes, central serous chorioretinopathy, and systemic disorders. Introductory chapters discuss the anatomy, pathophysiology, and imaging of PEDs, highlighting how especially the increasing use of spectral domain OCT enables even small PEDs to be detected and followed over time. The diverse forms of PED are then described, with explanation of how they may hint at the underlying pathology or even be pathognomonic when considered in conjunction with other clinical features. New insights are provided into the characteristics of the various forms of PED, and predictors of complications - such as rip of the PED - are discussed. It is clearly explained how knowledge of the different types of PED and their underlying diseases can assist in creating an appropriate individualized follow-up and therapy scheme for each patient |
| Bibliography |
Includes bibliographical references |
| Notes |
Print version record |
| Subject |
Retina -- Diseases.
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Diagnosis, Differential.
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Diagnosis, Differential
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Retinal Detachment -- diagnosis
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Retinal Detachment -- complications
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Retinal Detachment -- therapy
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Retinal Diseases
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MEDICAL -- Surgery -- General.
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Diagnosis, Differential
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Retina -- Diseases
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| Form |
Electronic book
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| Author |
Gamulescu, Maria-Andreea
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Helbig, Horst
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Wachtlin, Joachim
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| ISBN |
9783319561332 |
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3319561332 |
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