Structural Disorder and Its Connection with Misfolding Diseases; Intrinsic Disorder in Proteins Associated with Neurodegenerative Diseases; Dynamic Role of Ubiquitination in the Management of Misfolded Proteins Associated with Neurodegenerative Diseases; Protein Misfolding and Axonal Protection in Neurodegenerative Diseases; Endoplasmic Reticulum Stress in Neurodegeneration; Involvement of Alpha-2 Domain in Prion Protein Conformationally-Induced Diseases; Synuclein Structure and Function in Parkinson's Disease
Summary
Reviews the molecular events initiated by unfolded or misfolded proteins leading to conformational human diseases, with special emphasis on the macromolecular homo- and heteroassociations of the malfolded proteins into characteristic ultrastructures found primarily in Parkinson's and Alzheimer's diseases
