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Title The ubiquitin system in health and disease / editors, S. Jentsch, B. Haendler
Published Berlin ; London : Springer, 2009

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Description 1 online resource (xv, 190 pages) : illustrations (some color)
Series Ernst Schering Research Foundation symposium proceedings ; 2008/1
Ernst Schering Foundation symposium proceedings ; 2008/1.
Contents Crosstalk between the SUMO and ubiquitin pathways / T. Hunter, H. Sun -- A tale of two giant proteases / B. Rockel, W. Baumeister -- Molecular genetics of the ubiquitin-proteasome system: lessons from yeast / M. Hochstrasser, M. Deng, A.R. Kusmierczyk, X. Li, S.G. Kreft, T. Ravid, M. Funakoshi, M. Kunjappu, Y. Xie -- Less is more: how protein degradation regulates muscle development / T. Hoppe -- Transcriptional control and the ubiquitin-proteasome system / A. Leung, F. Geng, A. Daulny, G. Collins, P. Guzzardo, W.P. Tansey -- Ubiquitination of Myc: proteasomal degradation and beyond / J. Müller, M. Eilers -- Regulation of apoptosis and cytokinesis by the anti-apoptotic E2/E3 ubiquitin-ligase BRUCE / C. Pohl, S. Jentsch -- Dissecting roles of ubiquitination in the p53 pathway / J. Shan, C. Brooks, N. Kon, M. Li, W. Gu -- Regulation of T cell differentiation and allergic responses by the E3 ubiquitin ligase itch / Y.-C. Liu -- Approaches to discovering drugs that regulate E3 ubiquitin ligases / J. Huang, L. Tsvetkov, K. Qu, S. Daniel-Issakani, D.G. Payan -- Inhibiting Hdm2 and ubiquitin-activating enzyme: targeting the ubiquitin conjugating system in cancer / A.M. Weissman, Y. Yang, J. Kitagaki, C.A. Sasiela, J.A. Beutler, B.R. O'Keefe
Summary The ubiquitin system plays an essential role in numerous cellular processes by controlling protein stability and function. An understanding of the mechanisms governing these processes is likely to allow the identification of novel targets for pharmacological intervention. This work covers the developments in this field
Bibliography Includes bibliographical references
Notes Print version record
Subject Ubiquitin -- Congresses
Cellular control mechanisms -- Congresses
Ubiquitins -- physiology
Proteasome Endopeptidase Complex -- physiology
MEDICAL -- Histology.
Ubiquitins -- physiology.
Proteasome Endopeptidase Complex -- physiology.
Ubiquitines -- Congrès.
Régulation cellulaire -- Congrès.
Ubiquitin -- Pathophysiologie.
Ubiquitin -- Physiologie.
Physiologie.
Pathophysiologie.
Ubiquitin.
Cellular control mechanisms.
Ubiquitin.
Physiologie
Pathophysiologie
Ubiquitin
Ubiquitines -- Congrès.
Régulation cellulaire -- Congrès.
Genre/Form Conference papers and proceedings.
Conference papers and proceedings.
Actes de congrès.
Form Electronic book
Author Jentsch, S. (Stefan)
Haendler, B. (Bernard)
Ernst Schering Research Foundation.
ISBN 9783540851073
3540851070