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Book Cover

Title Uterine myoma, myomectomy and minimally invasive treatments / Andrea Tinelli, Antonio Malvasi, editors
Published Cham : Springer, [2014]


Description 1 online resource (xiii, 281 pages) : illustrations (some color)
Contents Preface; Contents; Contributors; 1: Pathophysiology of Uterine Myomas and Its Clinical Implications; Introduction; Prevalence and Histogenesis; Factors Influencing Growth of Leiomyomas; Estrogens (E); Progesterone (P); Growth Factors; Cytogenetics; High Mobility Group 1 Proteins; Uterine Inner and Outer Myometrium; Vascularization and Location of Uterine Myomas; Symptomatology of Uterine Myomas; Abnormal Uterine Bleeding; Infertility; Spontaneous Abortions; Pelvic Pain; Promising New Medical Therapeutic Agents; Progesterone Antagonists; Selective Progesterone Receptor Modulators (SPRMs)
AsoprisnilProellex (CDB-4124); Ulipristal Acetate (CDB-2914); Aromatase Inhibitors (AIs); Summary and Conclusions; References; 2: Genetic and Genomics of Uterine Myomas; Introduction; Molecular Aspect of Uterine Leiomyomas; The Genomic Landscape of Uterine Myomas: Mutation Analysis and Chromosome Rearrangements; Epigenetics in Myomas; Pathways Influencing Disease; Perspectives; References; 3: Uterine Myomas and Histopathology; Introduction; Particular Types of Leiomyomata; STUMP; References; 4: Uterine Fibroids: Clinical Features; Introduction; Incidence; Risk Factors; Clinical Presentation
Natural History of FibroidsDiagnosis; Treating Pre-operative Anemia; New Appearance of Fibroids; Uterine Changes Following Myomectomy; The Risk of Uterine Rupture After Myomectomy; References; 5: Uterine Myomas and Fertility; Introduction; Etiology, Pathophysiology and Genetic Origin; Etiology and Microscopy; Pathophysiology; Genetic Origin; Philosophy of Myomas in Infertility; Myomas and Fertility Outcome?; Implantation Rates; Recurrent Pregnancy Loss; Myomas During Pregnancy; Treatment Possibilities; Myomectomy and Fertility: Laparoscopic and Hysteroscopic Resection of Fibroids
General AspectsLaparoscopic Stepwise Enucleation of an Intramural Fibroid and Uterine Reconstruction; Hysteroscopic Myoma Enucleation Has to Be Performed According to the Depth of Infiltration into the Myometrium; Differentiation of Fibroids and Focal Endometriosis to Adenomatoid Tumors; Case 1; Case 2; Recurrence Rates; Fertility Outcome: Our Experience; Location of Myoma; Pregnancies and Deliveries; Mode of Delivery; Complications; Discussion and Conclusions; References; 6: Uterine Fibroid Pseudocapsule; Introduction; Anatomy of Fibroid Pseudocapsule
Neurotransmitters in Myoma PseudocapsuleComparison Between Myoma Pseudocapsule and Prostate Capsule; Intracapsular Myomectomy; The Functional Autonomy of Pseudocapsule and Its Impact on Muscular Healing; The Advantage of Endoscopically Tailored Myomectomy and Prostatectomy; The Rationale of Intracapsular Myomectomy: Pro and Cons; Conclusions; References; 7: Adenomyosis and Adenomyomata; Introduction; Historical Background; Histological Definition; Etiology of Adenomyosis; Diagnostic Methods and the Uterine Junctional Zone; Symptomatology and Types of Adenomyosis
Summary Uterine myomas are the most common benign tumors in women, affecting the half of women and mostly in reproductive age. Myomas cause significant morbidity and are the single most common indication for hysterectomy around the world. Thus, myomas represent a major personal and public health concern worldwide. The diagnosis of fibroids can be established based on ultrasound and radiological imaging. Recent research on the genomics and molecular biology of myomas has enabled us to better understand the pathogenesis and pathophysiology of this benign tumor, but more remains to be discovered. In the
Analysis chirurgie
public health
Medicine (General)
Geneeskunde (algemeen)
Notes Includes index
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (SpringerLink, viewed December 29, 2014)
Subject Myometrium -- Tumors -- Surgery
Leiomyoma -- physiopathology
Uterine Myomectomy -- methods
Minimally Invasive Surgical Procedures -- methods
Uterine Neoplasms -- surgery
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Form Electronic book
Author Tinelli, Andrea, editor.
Malvasi, Antonio, editor.
ISBN 9783319103051