| Description |
1 online resource (1025 pages) |
| Contents |
Front Cover; Contents; Preface; Part I -- Introduction; Chapter 1 -- Chemotherapeutic Engineering: Concept, Feasibility, Safety and Prospect-A Tribute to Shu Chien on His 82nd Birthday; Part II -- Chemotherapeutic Engineering: Concepts; Chapter 2 -- Chemotherapeutic Engineering: Application and Further Development of Chemical Engineering Principles for Chemotherapy of Cancer and Other Diseases; Chapter 3 -- New-Concept Chemotherapy by Nanoparticles of Biodegradable Polymers: Where Are We Now?; Chapter 4 -- Nanoparticles of Biodegradable Polymers for New-Concept Chemotherapy |
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Chapter 5 -- Nanoparticles of Biodegradable Polymers for Cancer TreatmentPart III -- Chemotherapeutic Engineering: Feasibility; Chapter 6 -- Chemotherapeutic Engineering: Vitamin E TPGS-Emulsified Nanoparticles of Biodegradable Polymers Realized Sustainable Paclitaxel Chemotherapy for 168 h in vivo; Part IV -- Chemotherapeutic Engineering: Further Proof-of Concept Experimental Results; Chapter 7 -- In vitro and in vivo Investigation on PLA-TPGS Nanoparticles for Controlled and Sustained Small Molecule Chemotherapy |
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Chapter 8 -- In vitro and in vivo Evaluation of Methoxy Polyethylene Glycol-Polylactide (MPEG-PLA) Nanoparticles for Small-Molecule Drug ChemotherapyChapter 9 -- The Drug Encapsulation Efficiency, in vitro Drug Release, Cellular Uptake and Cytotoxicity of Paclitaxel-Loaded Poly(Lactide)-Tocopheryl Polyethylene Glycol Succinate Nanoparticles; Chapter 10 -- Nanoparticles of Poly(D, L-Lactide)/Methoxy Poly(Ethylene Glycol)-Poly(D, L-Lactide) Blends for Controlled Release of Paclitaxel |
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Chapter 11 -- In vitro and in vivo Studies on Vitamin ETPGS-Emulsified Poly(D, L-Lactic-co-Glycolic Acid) Nanoparticles for Paclitaxel FormulationChapter 12 -- Nanoparticles of Poly(Lactide)/Vitamin E TPGS Copolymer for Cancer Chemotherapy: Synthesis, Formulation, Characterization and in vitro Drug Release; Chapter 13 -- A Novel Controlled Release Formulation for the Anticancer Drug Paclitaxel (Taxol®): PLGA Nanoparticles Containing Vitamin E TPGS |
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Chapter 14 -- Fabrication, Characterization and in vitro Release of Paclitaxel (Taxol®) Loaded Poly(Lactic-co-Glycolic Acid) Microspheres Prepared by Spray Drying Technique with Lipid/Cholesterol EmulsifiersChapter 15 -- Effects of Emulsifiers on the Controlled Release of Paclitaxel (Taxol®) from Nanospheres of Biodegradable Polymers; Part V -- Chemotherapeutic Engineering: Drug Targeting; Chapter 16 -- Copolymer Technology for Advanced Nanomedicine; Chapter 17 -- A Strategy for Precision Engineering of Nanoparticles of Biodegradable Copolymers for Quantitative Control of Targeted Drug Delivery |
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Chapter 18 -- Folic Acid Conjugated Nanoparticles of Mixed Lipid Monolayer Shell and Biodegradable Polymer Core for Targeted Delivery of Docetaxel |
| Summary |
This book is a collection of the major publications of the authors in the emerging area of chemotherapeutic engineering. It describes and demonstrates the concept, feasibility, safety and prospect of chemotherapeutic engineering through a full spectrum of proof-of-concept experiments from design, characterization, in vitro cellular uptake, cytotoxicity, to in vivo pharmacokinetics, biodistribution, and xenograft tumor model of the various nanocarriers, such as prodrugs, micelles, liposomes, and nanoparticles of biodegradable polymers |
| Bibliography |
Includes bibliographical references at the end of each chapters |
| Notes |
Print version record |
| Subject |
Pharmaceutical chemistry.
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Antineoplastic agents.
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Antimitotic agents.
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Neoplasms -- drug therapy
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Chemistry, Pharmaceutical
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Antimitotic Agents
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Antineoplastic Agents
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MEDICAL -- Pharmacology.
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Antimitotic agents
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Antineoplastic agents
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Pharmaceutical chemistry
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| Form |
Electronic book
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| Author |
Feng, Si-Shen, editor
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Chong, Stanford, editor
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Rompas, Jenny, editor
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| ISBN |
9789814463157 |
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9814463159 |
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9814463140 |
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9789814463140 |
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