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Book Cover
E-book

Title The HDL handbook : biological functions and clinical implications / edited by Tsugikazu Komoda
Edition Third edition
Published London : Elsevier Ltd. : Academic Press, [2017]
©2017

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Description 1 online resource
Contents Molecular mechanisms of hyperalphalipoproteinemia / Shizuya Yamashita, Daisaku Masuda, Tohru Ohama and Masahiro Koseki -- CETP deficiency and concerns in CETP inhibitor development / Akhiro Inazu -- Degenerated HDL and its clinical implications / Hirokazu Honda, Toshiyuki Matsunaga and Tsugikazu Komoda -- HDL Apoprotein mimetic peptides as antiinflammatory molecules / Godfrey S. Getz and Catherine A. Reardon -- Reverse cholesterol transport in HDL metabolism / Maryse Guerin -- Role of ATP-Binding cassette transporters A1 and G1 in reverse cholesterol transport in altherosclerosis / Kazuhiro Nakaya, Makoto Ayaori and Katsunori Ikewaki -- Sphingosin-1-phosphate and HDL metabolism / Xian-Cheng Jiang and Zhiqiang Li -- Role of SR-BI in HDL metabolism / Herbert Stangl and Witta Monika Strobl -- Paroxonase 1 and its clinical relevance / Alejandro Gugliucci -- MicroRNA regulation of HDL homeostasis / Xinghui Sun and Mark W. Feinberg -- The application of proteomic techniques in the study of HDL particle characterization and biomarker discovery / Elena Burillo, Inmaculada Jorge, Diego Martínez-López, Emilio Camafeita, Jesus Vazquez and Jose L. Martin-Ventura -- Therapies targeting HDLc levels and HDL function / Cecelia Vitali and Marina Cuchel
Summary The HDL Handbook: Biological Functions and Clinical Implications, Third Edition, brings laboratory research in HDL from bench to bedside in a reference format for both researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. Information presented is valuable for the development of clinical trials with the aim of improvement of HDL-C levels and the prevention of cardiovascular events. Highlights of this new edition include the science underpinning HDL metabolism including information on HDL-C metabolism, gene expression, gene-bioactive compounds interaction, and post-translational modifications of gene expression of apo-lipoproteins
Bibliography Includes bibliographical references and index
Notes Vendor-supplied metadata
Subject High density lipoproteins -- Handbooks, manuals, etc
Cholesterol, HDL -- physiology
Cholesterol Ester Transfer Proteins -- metabolism
Cholesterol, HDL -- metabolism
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
High density lipoproteins.
Genre/Form Computer network resources
Handbooks and manuals.
Handbooks and manuals.
Guides et manuels.
Form Electronic book
Author Komoda, Tsugikazu, editor.
ISBN 9780128125144
0128125144