| Description |
1 online resource (267 p.) |
| Series |
New York Academy of Sciences Ser |
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New York Academy of Sciences Ser
|
| Contents |
Cover -- Title Page -- Copyright -- Dedication -- Contents -- Acknowledgment -- Part I Introduction -- Chapter 1 Introduction -- 1.1 Receptors and Signaling -- 1.1.1 General Aspects of Signaling -- 1.1.2 Verbal and Physiological Signals -- 1.1.3 Criteria for Recognizing Transmitters and Receptors -- 1.1.4 Agonists -- 1.1.5 Receptors -- 1.1.6 Receptor-Enzyme Similarities -- 1.2 Types of Receptors and Hormones -- 1.2.1 Receptor Superfamilies -- 1.3 Receptors Are the Chemical Expression of Reality -- Chapter 2 The Origins of Chemical Thinking -- 2.1 Overview of Early Pharmacological History |
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2.1.1 The Development of a Chemical Hypothesis -- 2.1.2 Chemical Structure and Drug Action -- 2.1.3 The Site of Drug Action -- 2.2 Modern Pharmacology -- 2.2.1 Langley and Ehrlich: the Origins of the Receptor Concept -- 2.2.2 Maturation of the Receptor Concept -- 2.3 Phylogenetics of Signaling -- 2.3.1 The First Communicators -- Part II Fundamentals -- Chapter 3 Membranes and Proteins -- 3.1 Membranes -- 3.1.1 The Cytoplasmic Membrane -- the Importance of Cell Membranes -- 3.1.2 History of Membrane Models -- 3.1.2.1 The Roles of Proteins in Membranes |
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3.1.2.2 Challenges to the Danielli-Davson Model -- 3.1.2.3 A New View of Membrane Proteins -- 3.1.2.4 The Modern Concept of Membranes -- the Fluid Mosaic Model -- 3.1.3 Membrane Components -- 3.1.3.1 Membrane Lipids -- 3.1.3.2 Asymmetry and Heterogeneity in Membrane Lipids -- 3.1.3.3 Membrane Construction and Insertion of Proteins -- 3.2 The Nature and Function of Proteins -- 3.2.1 Linear and Three-Dimensional Structures -- 3.2.2 Primary Structure -- 3.2.3 Secondary Structure -- 3.2.4 Tertiary Structure -- 3.2.5 Protein Domains -- 3.2.6 Proteomics -- Chapter 4 Hormones as First Messengers |
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4.1 Hormones and Cellular Communication -- 4.1.1 Discovery of Hormones -- 4.2 Types of Hormones -- 4.2.1 Pheromones for Signaling between Individuals -- 4.2.2 Archaea and Bacteria -- 4.2.3 Eukaryotes -- 4.2.3.1 Chromalveolates -- 4.2.3.2 Unikonts -- Amoebozoa, Fungi, Animals -- 4.2.3.3 Invertebrate Pheromones -- 4.2.3.4 Vertebrate Pheromones -- 4.3 Vertebrate Hormones and Transmitters -- 4.3.1 Peptide and Non-Peptide Agonists -- 4.3.1.1 Peptides -- 4.3.1.2 Non-peptides -- 4.3.2 Peptide Hormones of the G-Protein-Coupled Receptors -- 4.3.2.1 Hypothalamic-Pituitary Axis |
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4.3.2.2 The Anterior Pituitary Trophic Hormones -- 4.3.3 Other Neural Peptides -- 4.3.3.1 Opioids -- 4.3.3.2 Non-Opioid Transmitter Peptides -- 4.3.4 Peptides from Non-Neural Sources -- 4.3.4.1 Digestive Tract Hormones -- 4.3.4.2 Hormones from Vascular Tissue -- 4.3.4.3 Hormones from the Blood -- 4.3.4.4 Peptide Hormones from Reproductive Tissues -- 4.3.4.5 Hormones from Other Tissues -- 4.3.5 Non-Peptides Acting on G-Protein-Coupled Receptors -- 4.3.5.1 Transmitters Derived from Amino Acids -- 4.3.5.2 Transmitters Derived from Nucleotides |
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4.3.5.3 Transmitters Derived from Membrane Lipids -- Prostaglandins and Cannabinoids |
| Notes |
Description based upon print version of record |
| Genre/Form |
Electronic books
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| Form |
Electronic book
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| ISBN |
9783527800155 |
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3527800158 |
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