| Description |
1 online resource (214 p.) |
| Series |
Neuroendoscopy and Interventional Pain Medicines Series |
|
Neuroendoscopy and Interventional Pain Medicines Series
|
| Contents |
Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Preface -- List of Contributors -- The Implications of Low Back Pain on Prolonged Lifespan and Future Targeted Care Models to Support the Pursuit of Healthy Longevity -- Álvaro Dowling1,* and Kai-Uwe Lewandrowski2,3,4 -- INTRODUCTION -- Commercialization -- Aging -- Degenerative Musculoskeletal Diseases -- Precision Medicine -- Targeted Care Models -- CONCLUSION -- REFERENCES -- Current Concepts and Limits of Cell-Based Regeneration Strategies for Degenerative Disc Disease |
|
Alvaro Dowling1,*, Marcelo Molina2, William Omar Contreras López3,*, Morgan P. Lorio4, Stefan Landgraeber5, Jorge Felipe Ramírez León6,7,8 and Kai-Uwe Lewandrowski9,10,11 -- INTRODUCTION -- Normal Structures and Natural Healing -- Normal Structure of the Intervertebral Disc -- Pathophysiology -- Mesenchymal Stem Cells -- Adipose-Derived Stem Cells -- The Difference between White and Brown Adipose Tissue -- Harvesting -- Stem Cell Formation and Identification -- Mesenchymal Stem Cell Injection for DDD -- Mechanism of Action of MSCs for DDD -- MSC Clinical Trials |
|
Functional versus Structural Improvements -- The Ethics of MSC Therapies -- CONCLUSION -- REFERENCES -- Current Clinical Applications of Regenerative Strategies for Lumbar Degenerative Disc Disease and Global Disease Burden Due to Low Back Pain -- Álvaro Dowling1, Marjan Asefi2, Jaime Moyano3, Jorge Felipe Ramírez León4,5,6, Kai-Uwe Lewandrowski7,8,9 and William Omar Contreas López10,* -- INTRODUCTION -- Global Disease Burden -- Degenerative Disc Disease -- The Molecular Basis of Disc Degeneration -- Regenerative Strategies -- Platelet-Rich Plasma (PRP) |
|
Autologous Bone Marrow Mesenchymal Stem Cells -- Current Evidence for Biologics in Clinical Management of Low Back Pain -- CONCLUSION -- REFERENCES -- Current Bioengineering Strategies for Injured or Degenerative Intervertebral Discs -- Alvaro Dowling1,* and Marcelo Molina2 -- INTRODUCTION -- Annulus Fibrosus Repair -- Tissue Engineering for Annular Repair -- Nucleus Augmentation and Injectables -- Nucleus Replacement and Regeneration -- Biomaterials -- Annulus Fibrosus/nucleus Pulposus Bioengineering Strategies -- DISCUSSION -- CONCLUSION -- REFERENCES |
|
Current Therapy Strategies for Vertebral Endplates -- Alvaro Dowling1,* and Marcelo Molina2 -- INTRODUCTION -- Physiology -- Endplate and Skeletal Maturity -- Vascularity -- Neuroanatomy of the Vertebral Endplate -- Endplate Failure Modes -- Rationale for Endplate Treatment -- Increasing Endplate Vascularity -- Enhanced Biointegration -- Clinical Studies -- DISCUSSION -- CONCLUSION -- REFERENCES -- The Current Concept for Stem Cell Therapy in Spinal Cord Injury -- Alvaro Dowling1,* and Marcelo Molina2 -- INTRODUCTION -- Primary Injury -- Secondary Injury -- Chronic Phase and Neurodegeneration |
| Summary |
Neuroendoscopy and Interventional Pain Medicine is a clinically focused medical monograph series. With contributions from a team of internationally recognized neurosurgeons and spinal surgery specialists, the series aims to illuminate the latest advancements in minimally invasive neurosurgical techniques and pain management. Each volume offers invaluable insights into the future of minimally invasive treatments in this medical subspecialty. Interventional Pain |
| Notes |
Description based upon print version of record |
|
American Spinal Cord Injury Association Scale |
| Form |
Electronic book
|
| Author |
Contreras, William Omar
|
|
Ramírez, Jorge Felipe
|
| ISBN |
9789815274462 |
|
9815274465 |
|
