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Book Cover
E-book
Author Mouleeswaran, K. S., author

Title Atlas of basic liver histology for practicing clinicians and pathologists / K. S. Mouleeswaran, Joy Varghese, Mettu Srinivas Reddy
Published Singapore : Springer, [2023]

Copies

Description 1 online resource (xiii, 116 pages)
Contents Intro -- Preface -- Contents -- About the Authors -- 1: Basic Liver Histology -- 1.1 Liver Cell Plate -- 1.2 Zones of Liver -- 1.3 Basic Cell Types -- 1.3.1 Hepatocytes -- 1.3.2 Cholangiocytes -- 1.3.3 Kupffer Cells (KC) -- 1.4 Limiting Plate -- 1.5 Portal Tract -- 1.6 Central Vein -- 1.7 Sinusoids -- 1.8 Biliary Canaliculi -- 1.9 Special Stains -- 1.9.1 Masson Trichome (MT) Stain -- 1.9.2 Reticulin Stain -- 1.9.3 PAS (Periodic Acid Schiff) Stain and PAS-D (Periodic Acid Schiff with Diastase) Stain -- 1.9.4 Orcein Stain -- 1.9.5 Rhodanine Stain -- 1.9.6 Perl's Stain
2: Basic Liver Pathology Terminologies -- 2.1 Cholestasis -- 2.1.1 Bland Canalicular Cholestasis -- 2.1.2 Hepatocellular Cholestasis and Canalicular Cholestasis -- 2.2 Pigment Deposits -- 2.2.1 Dubin-Johnson Pigments -- 2.2.2 Iron Pigments -- 2.2.2.1 Iron in Ductal Epithelial Cells (Perls Stain) -- 2.2.2.2 Hepatocellular and Kupffer Cell Iron Overload (Grade 3 Siderosis) -- 2.2.3 Copper and Copper Associated Proteins -- 2.2.3.1 Rhodanine Stain for Copper Deposits -- 2.3 Portal Inflammation -- 2.3.1 Mild Portal Inflammation -- 2.3.1.1 Portal Inflammation with Ductular Reaction
2.3.2 Moderate Portal Inflammation -- 2.3.3 Severe Portal Inflammation and Interface Hepatitis -- 2.3.4 Interface Hepatitis and Focal Emperipolesis -- 2.3.5 Lobular Inflammation -- 2.3.6 Portal Inflammation with Predominant Lymphocytes -- 2.3.7 Portal Inflammation with Predominant Neutrophils -- 2.3.8 Portal Inflammation with Predominant Eosinophils -- 2.3.9 Lymphoplasmacytic Infiltration at Portal Tract -- 2.4 Bile Duct Pathology -- 2.4.1 Ductopenia (Absence of Duct in the Portal Tract) -- 2.4.1.1 Ductopenia in PAS -- 2.4.2 Periductal Lamellar Fibrosis
2.4.2.1 Periductal Lamellar Fibrosis (Masson Trichrome Stain) -- 2.4.3 Neutrophilic Ductulitis -- 2.4.4 Lymphocytic Ductulitis -- 2.5 Fatty Change in Liver Disease -- 2.5.1 Macrovesicular Fatty Change -- 2.5.2 Micro and Macrovesicular Fatty Change -- 2.6 Central Perivenulitis -- 2.7 Necrosis -- 2.7.1 Bridging Necrosis -- 2.7.2 Confluent Necrosis -- 2.7.3 Lobular Inflammation with Spotty Necrosis -- 2.7.4 Submassive to Massive Necrosis in Explant Liver -- 2.7.5 Submassive to Massive Necrosis in Core Needle Biopsy -- 2.8 Extramedullary Hematopoesis -- 2.9 Multinucleated Giant Cell
2.10 Ballooning Degeneration of Hepatocyte -- 2.11 Mallory Denk Bodies with Cholestasis -- 2.11.1 Mallory Denk Body in HCC -- 2.12 Adequacy of Liver Biopsy -- 3: Pediatric Liver Pathology -- 3.1 Neonatal Hepatitis Syndrome -- 3.1.1 Histology -- 3.2 Extra Hepatic Biliary Atresia -- 3.2.1 Histology -- 3.2.1.1 Salient Histological Features -- 3.2.1.2 Bile Duct Pictures for EHBA -- 3.3 Paucity of Intrahepatic Bile Ducts: Alagille Syndrome -- 3.3.1 Histology -- 3.3.1.1 Salient Histopathological Features -- 3.4 Ductal Plate Malformation Disorders
Summary The book provides a visual run-through of liver pathology through high-quality images from the healthy liver through acute liver injury to chronic liver disease - stressing on common mechanisms for specific histological appearances, correlating them with clinical features and laboratory investigations to reach the diagnosis. Individual chapters in this richly illustrated atlas cover the wide gamut of liver disease, including types of liver injury, viral hepatitis, fatty liver disease and its complications, vascular and autoimmune liver diseases, pediatric liver diseases, liver tumors, and finally, pathology of the transplanted liver. This book bridges the gap by integrating basic clinical information with histopathological findings, as existing books cater primarily to the pathologists needs and do not provide sufficient clinical background to engage the clinician. It serves as a quick guide for adult and pediatric hepatologists, liver surgery doctors, pathologists as well as trainees in gastroenterology, hepatology, gastrointestinal surgery, liver transplantation and pediatric gastroenterology
Notes 3.4.1 Congenital Hepatic Fibrosis (CHF)
Description based on online resource; title from digital title page (viewed on November 13, 2023)
Subject Liver -- Histology -- Atlases
Genre/Form atlases.
Atlases.
Atlas.
Form Electronic book
Author Varghese, Joy, author
Reddy, Mettu Srinivas, author
ISBN 9789819957620
9819957621