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E-book

Title Lyme carditis : from A to Z / Adrian Baranchuk, Rachel Wamboldt, Chang Nancy Wang, editors
Published Cham : Springer, [2023]

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Description 1 online resource (164 p.)
Contents Intro -- Foreword -- Contents -- Introduction -- 1 Introduction -- References -- Lyme Diseases Epidemiology: Update 2022 -- 1 Introduction -- 2 Transmission and Life Cycle -- 3 Demographics -- 4 Global Geographical Distribution of Lyme Disease -- 4.1 North America -- 4.2 Europe -- 4.3 Asia -- 5 Risk Factors for Human Infection Associated with Geographical and Environmental Conditions -- References -- Etiopathogenesis of Lyme Carditis -- 1 Introduction -- 2 Pathogenesis -- 2.1 Transmission of Lyme Disease to Human -- 2.2 Direct Invasion of Myocardial Tissues
2.3 Inflammation and Borrelia burgdorferi -- 3 Conductive Disease and Arrhythmias -- 3.1 Lyme Endocarditis -- 4 Myocarditis and Pericarditis -- 5 Dilated Cardiomyopathy -- 6 Conclusion -- References -- Stages of Lyme Disease -- 1 Introduction -- 2 Early Localized Lyme Disease (Stage 1) -- 2.1 Erythema Migrans Rash -- 2.2 Other Acute Symptoms -- 2.3 Early Laboratory Diagnosis -- 2.4 Asymptomatic Infection -- 3 Early Disseminated Lyme Disease (Stage 2) -- 3.1 Multiple Erythema Migrans Lesions -- 3.2 Neurologic Lyme Disease -- 3.3 Cardiac Disease -- 3.4 Musculoskeletal Signs and Symptoms
4 Late Lyme Disease (Stage 3) -- 4.1 Late Lyme Arthritis -- 4.2 Late Neurologic Disease -- 4.3 Probable Late Lyme Disease -- 5 Post-treatment Outcomes -- 5.1 Chronic Lyme Disease -- 5.2 Post-treatment Lyme Disease -- 5.3 Post-infectious Lyme Arthritis -- 6 Conclusions -- References -- Pathophysiology of Early Disseminated Lyme Carditis -- 1 Introduction -- 2 Method of Transmission -- 3 Pathophysiological Mechanisms -- 4 Direct Invasion of Myocardial Tissue by B. Burgdorferi -- 5 Proteins Involved in Spirochete Invasion -- 6 Exaggerated Inflammatory Response -- 7 Maladaptive Immune Response
8 Conclusions -- References -- Clinical Manifestations of Early Disseminated Lyme Carditis -- 1 Introduction -- 2 Pathophysiology -- 3 Clinical Findings-Early Disseminated Lyme Carditis (EDLC) -- 3.1 General Symptoms -- 3.2 Atrioventricular Conduction Abnormalities -- 3.3 Myocarditis/Pericarditis -- 3.4 Miscellaneous Abnormalities -- 4 Diagnosis -- 5 Treatment -- 6 Prognosis -- 7 Conclusion -- References -- Differential Diagnosis of Unexpected Atrioventricular Blocks and Application of the SILC Score -- 1 Introduction -- 2 Brief Anatomy and Physiology of the Atrioventricular Junction
3 Causes of Atrioventricular Block -- 4 Infectious Diseases -- 4.1 Lyme Disease -- 4.2 Rheumatic Fever -- 4.3 Tuberculosis -- 4.4 Chagas Disease -- 4.5 Infective Endocarditis -- 5 Infiltrative Diseases -- 5.1 Sarcoidosis -- 5.2 Amyloidosis -- 5.3 Hemochromatosis -- 6 Autoimmune Disorders -- 7 Conclusion -- References -- Diagnosis and Management of Lyme Carditis -- 1 Introduction -- 2 Signs and Symptoms -- 3 Diagnosis -- 3.1 Conduction Abnormalities -- 3.2 Endocarditis -- 3.3 Dilated Cardiomyopathy -- 4 Management -- 4.1 SILC Score and Antibiotic Therapy -- 4.2 Pacing for High Degree AVB
Summary This book provides valuable tools for the appropriate diagnosis and management of Lyme carditis. It includes epidemiological, pathophysiological and clinical recommendations for the identification, confirmation and management of the disease. With one score that currently facilitates diagnosing Lyme carditis when patients present with undiagnosed complete heart block (the SILC Score), a rapid recognition of Lyme carditis as the cause of conduction disorders is essential to allow early treatment with IV antibiotics with a high probability of complete resolution and avoiding unnecessary pacemaker implantation. Lyme carditis: From A to Z provides a clinical algorithm to facilitate management, pre-discharge evaluations of the conduction system and long-term follow-up of patients properly treated for Lyme carditis. It provides a proven approach to patients implanted with cardiac devices and in whom Lyme carditis is subsequently diagnosed, while it also explores the possibility of Lyme dilated cardiomyopathy as a chronic manifestation of Lyme disease. This book therefore represents an original and unique resource that sheds light on an important topic of discussion in many endemic regions of the world
Notes 4.3 Additional Considerations
Includes index
Online resource; title from PDF title page (SpringerLink, viewed November 6, 2023)
Subject Heart -- Diseases.
Lyme disease -- Complications
Heart Diseases
Heart -- Diseases.
Form Electronic book
Author Baranchuk, Adrian.
Wamboldt, Rachel.
Wang, Chang Nancy
ISBN 9783031411694
3031411692