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Title Horizons in cancer research. Volume 61 / Hiroto S. Watanabe, editor
Published New York : Nova Biomedical, [2016]
©2016
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Description 1 online resource (196 pages)
Series Horizons in cancer research
Horizons in cancer research.
Contents HORIZONS IN CANCER RESEARCH VOLUME 61 ; HORIZONS IN CANCER RESEARCH VOLUME 61 ; Library of Congress Cataloging-in-Publication Data; CONTENTS; PREFACE; Chapter 1 SEARCHING FOR A MAGIC KEY IN ONCOLOGY CONTINUES ; ABSTRACT; 1. WHAT IS THE ESSENCE OF THE CANCER CELL? ; 2. PRESUMPTIVE COMMON TRIGGER MECHANISM OF ACTION OF DIFFERENT CARCINOGENS; 3. DIFFERENT STEPS OF TUMOROUS PROGRESSION STAGE ; 3a. Invasion ; 3b. Metastasis ; 4. CELLS SPONTANEOUS MALIGNIZATION IN TISSUE CULTURE ; 5. ARISING OF TUMORS IN TRANSPLANTATION OF ALLOGENIC INTERNAL ORGANS ; 6. REASON OF ARISING OF TUMORS IN AIDS
7. POSSIBLE CORRELATION BETWEEN BACTERIAL MEMBRANOTOXINS AND MALIGNANT NEOPLASMS 8. REASON OF ARISING OF TUMORS IN HEMOLYTIC ANEMIAS ; 9. ARISING OF MALIGNANT NEOPLASMS BY SOME NON-CARCINOGENIC SUBSTANCES ; 9a. Fatty Acids ; 9b. Carbohydrates; 9c. Distilled Water ; 9d. Saline; CONCLUSION ; REFERENCES; Chapter 2 MECHANISMS OF CANCER FORMATION UNDER INTERPLAY BETWEEN HOST IMMUNITY AND HUMAN PAPILLOMAVIRUS (HPV) INFECTION ; ABSTRACT ; INTRODUCTION ; HPV TYPES ; HPV GENOME ; HPV LIFE CYCLE; MECHANISMS OF HPV ENTRY ; MHC CLASS I AND HPV IMMUNE EVASION ; IMMUNE RESPONCES IN HPV INFECTION
BASIC FUNCTIONS OF E6 AND E7 IN ONCOGENESIS TRANSFORMING FUNCTIONS OF E7 IN ONCOGENESIS ; TRANSFORMING FUNCTIONS OF E6 IN ONCOGENESIS ; MECHANISMS OF INFLAMMATION TO CANCER FORMATION ; ACKNOWLEDGMENT ; REFERENCES ; Chapter 3 MONOCLONAL GAMMOPATHIES: FROM MGUS TO MULTIPLE MYELOMA; ABSTRACT ; 1. INTRODUCTION ; 2. PHYSIOPATHOLOGY AND EVOLUTION; 2.1. Intraclonal Heterogeneity in Multiple Myeloma ; 2.2. Genetics and Epigenetics from MGUS to MM ; 2.2.1. Genetic Alterations in MM ; t(4; 14) ; t(11; 14) ; t(14; 16) ; t(14; 18) ; Chromossome 1 ; del(13) ; del(17p) ; Del(8p)
Other Chromosomic Alterations 2.2.2. Epigenetic Alterations; 2.3. Proliferation and Survival Pathways -- The Role of Microenvironment ; 2.4. Bone Marrow Microenvironment ; Bone Marrow Stem Cells ; Mesenchymal Stem Cells ; The Osteoblastic/Osteoclastic Niche ; The Vascular/Endothelial Niche ; Lymphocytes ; Other Cells ; CONCLUSION ; REFERENCES ; Chapter 4 CHOLINE METABOLISM AND INTRACELLULAR SIGNALING IN CANCER; ABSTRACT ; INTRODUCTION ; IN-VITRO MEASUREMENT OF CHOLINE METABOLISM ; IN-VIVO MEASUREMENT OF CHOLINE METABOLISM ; MOLECULAR PET IMAGING OF CHOLINE METABOLISM
TUMOR CHOLINE METABOLISM MAY NOT CORRELATE WITH TUMOR GROWTH ROLE OF CHOLINE METABOLITES IN CELL SIGNAL TRANSDUCTION ; REGULATION OF CHOLINE METABOLISM BY RAS AND RAS-LIKE ONCOGENES; EFFECT OF MOLECULES DOWNSTREAM OF RAS ON CHOLINE METABOLISM; EFFECT OF MITOGEN ACTIVATED PROTEIN KINASE PATHWAYS ON CHOLINE METABOLISM ; INTERACTIONS BETWEEN THE PI3K/AKT PATHWAY AND CHOLINE METABOLISM ; CONCLUSION ; REFERENCES ; Chapter 5 THE CORRELATION BETWEEN ANATOMIC SITES OF THE MELANOMA DISTRIBUTION ON THE UPPER BACK AREA AND LACK OF SUNSCREEN APPLICATION ; ABSTRACT ; INTRODUCTION
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Cancer -- Research.
Cancer -- Treatment.
Form Electronic book
Author Watanabe, Hiroto S., editor
ISBN 1634845366 (electronic bk)
9781634845366 (electronic bk)