Limit search to available items
5801 results found. Sorted by relevance | date | title .
Book Cover
E-book
Author Lecca, Paola, 1973-

Title Identifiability and regression analysis of biological systems models : statistical and mathematical foundations and R scripts / Paola Lecca
Published Cham : Springer, ©2020

Copies

Description 1 online resource (90 pages)
Series SpringerBriefs in statistics, 2191-5458
SpringerBriefs in statistics
Contents 1 Complex systems and sets of data -- 2 Dynamic models -- 3 Model identifiability -- 4 Relationships between phenomena -- 5 Codes
Summary This richly illustrated book presents the objectives of, and the latest techniques for, the identifiability analysis and standard and robust regression analysis of complex dynamical models. The book first provides a definition of complexity in dynamic systems by introducing readers to the concepts of system size, density of interactions, stiff dynamics, and hybrid nature of determination. In turn, it presents the mathematical foundations of and algorithmic procedures for model structural and practical identifiability analysis, multilinear and non-linear regression analysis, and best predictor selection. Although the main fields of application discussed in the book are biochemistry and systems biology, the methodologies described can also be employed in other disciplines such as physics and the environmental sciences. Readers will learn how to deal with problems such as determining the identifiability conditions, searching for an identifiable model, and conducting their own regression analysis and diagnostics without supervision. Featuring a wealth of real-world examples, exercises, and codes in R, the book addresses the needs of doctoral students and researchers in bioinformatics, bioengineering, systems biology, biophysics, biochemistry, the environmental sciences and experimental physics. Readers should be familiar with the fundamentals of probability and statistics (as provided in first-year university courses) and a basic grasp of R
Bibliography Includes bibliographical references
Notes Print version record
Subject Regression analysis.
Biochemistry -- Statistical methods
Systems biology -- Statistical methods
Regression Analysis
Análisis de regresión
Bioquímica -- Métodos estadísticos
Regression analysis
Form Electronic book
ISBN 3030412555
9783030412555
9783030412562
3030412563