| Description |
1 online resource (413 p.) |
| Series |
Advances in Pharmaceutical Technology Ser |
|
Advances in Pharmaceutical Technology Ser
|
| Contents |
Cover -- Title Page -- Copyright -- Contents -- List of Contributors -- Series Preface -- List of Abbreviations -- Chapter 1 Selecting a Particle Sizer for the Pharmaceutical Industry -- 1.1 Introduction -- 1.1.1 Relevance of Particle Size in the Pharmaceutical Industry -- 1.1.2 Main Goals -- 1.1.3 Why it is So Difficult to Select a Particle Sizer -- 1.2 Particle Size Distribution -- 1.2.1 Equivalent Diameter -- 1.2.2 Reporting Particle Size -- 1.2.3 Distribution Statistics -- 1.3 Selecting a Particle Sizer -- 1.3.1 Classification -- 1.3.2 Selection Criteria |
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1.4 Aspects of Some Selected Methods -- 1.4.1 Optical Microscopy-based Methods -- 1.4.2 Laser Light-scattering Techniques -- 1.4.3 The Time-of-Flight Counter -- 1.4.4 Cascade Impactor -- 1.5 Conclusions -- 1.5 Acknowledgements -- 1.5 References -- Chapter 2 Spectroscopic Methods in Solid-state Characterization -- 2.1 Solid-state Structure of Particulates -- 2.2 Spectroscopy Overview -- 2.3 Spectroscopic Data Analysis -- 2.3.1 Band Assignment -- 2.3.2 Statistical Analysis -- 2.4 Infrared Spectroscopy -- 2.4.1 Principle -- 2.4.2 MIR Applications -- 2.4.3 MIR Imaging |
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2.5 Near-infrared Spectroscopy -- 2.5.1 Principle -- 2.5.2 NIR Applications -- 2.5.3 NIR Imaging -- 2.6 Terahertz Spectroscopy -- 2.6.1 Principle -- 2.6.2 Terahertz Applications -- 2.6.3 Terahertz Imaging -- 2.7 Raman Spectroscopy -- 2.7.1 Principle -- 2.7.2 Raman Applications -- 2.7.3 Raman Imaging -- 2.8 Nonlinear Optics -- 2.8.1 Principle -- 2.8.2 Nonlinear Optics Applications -- 2.8.3 Nonlinear Optical Imaging -- 2.9 Fluorescence Spectroscopy -- 2.9.1 Principle -- 2.9.2 Fluorescence from Solid-state Samples -- 2.9.3 Intrinsic Fluorophores in Solid Samples -- 2.9.4 Fluorescence Imaging |
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2.9.5 Fluorescence Lifetime Imaging Microscopy -- 2.10 Solid-state Nuclear Magnetic Resonance -- 2.10.1 The Basic Theory of NMR Spectroscopy -- 2.10.2 Solid-state NMR Technique -- 2.10.3 Solid-state NMR Experiments -- 2.10.4 Pharmaceutical Applications of Solid-state NMR -- 2.11 Conclusions -- 2.11 References -- Chapter 3 Microfluidic Analysis Techniques for Safety Assessment of Pharmaceutical Nano- and Microsystems -- 3.1 Microfluidic Bioanalytical Platforms -- 3.2 Microfabrication Methods and Materials -- 3.3 Microfluidic Cell Cultures |
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3.3.1 Selection of the Microfabrication Material by Design -- 3.3.2 Additional Design Considerations -- 3.3.3 Characterization of Pharmaceutical Nano- and Microsystems Using Organ-on-a-chip -- 3.4 Immobilized Enzyme Microreactors for Hepatic Safety Assessment -- 3.4.1 Nanoparticle Impacts on the Hepatic Clearance of Xenobiotics -- 3.4.2 Cytochrome P450 Interaction Studies in Through-flow Conditions -- 3.5 Microfluidic Total Analysis Systems -- 3.5.1 Microfluidic Separation Systems -- 3.5.2 Toward n-in-one Analytical Platforms -- 3.6 Epilogue -- 3.6 References |
| Notes |
Description based upon print version of record |
| Form |
Electronic book
|
| Author |
Douroumis, Dennis
|
|
Fahr, Alfred
|
|
Siepmann, Jürgen
|
|
Snowden, Martin J
|
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Torchilin, Vladimir
|
| ISBN |
9781119414025 |
|
1119414024 |
|
