| Description |
1 online resource (759 p.) |
| Contents |
Intro -- Preface -- Contents -- Editors and Contributors -- Part I: Bioactive Compounds from Endophytic Fungi -- Chapter 1: Recent Advances in Pharmaceutically Important Compounds from Endophytic Fungi -- 1 Introduction -- 2 Biomes, Regions, and Plant Families -- 3 Handling Endophytic Fungi -- 4 Innovative Pharmacological Targets for Bioactive Fungal Metabolites -- 5 Promising Endophytic Fungi Metabolites Recently Described -- 6 Developments Related to Bioactive Metabolites from Endophyte Fungi -- 7 Perspectives -- References |
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Chapter 2: Recent Advances in Anti-Infective Compounds Produced by Endophytic Fungi -- 1 Introduction -- 2 Role of Endophytic Research with Respect to Drug Discovery -- 3 Antibacterial Metabolites -- 3.1 Antimycobacterial Compounds from Endophytes -- 4 Antifungal Metabolites -- 5 Antiviral Metabolites -- 6 Antiprotozoal Metabolites -- 6.1 Antimalarial Metabolites -- 6.2 Anti-Leishmanial Metabolites -- 6.3 Anti-Trypanosomal Metabolites -- 7 Future Prospects and Challenges -- References -- Chapter 3: Fungal Endophytes: An Accessible Natural Repository for Discovery of Bioactive Compounds |
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1 Endophytic Natural Products (ENPs): An Introduction -- 1.1 Endophytes as a Treasure Hunt for ENPs -- 1.2 Polyketides, an Important Class of Bioactive ENPs -- 1.3 Small Peptides as Bioactive ENPs -- 2 ENPs with Anticancer Potential -- 3 ENPs with Antimicrobial Potential -- 4 Molecular Crosstalk Underlying ENPs Production -- 5 Conclusion -- References -- Part II: Endolichenic Fungi: a Source of New Chemical Entities -- Chapter 4: Endolichenic Fungi as a Source of Pharmaceutically Active Compounds -- 1 Introduction -- 2 Pharmaceutically Active Compounds Isolated from Endolichenic Fungi |
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2.1 Cytotoxic Compounds Isolated from Endolichenic Fungi -- 2.2 Antifungal Compounds Isolated from Endolichenic Fungi -- 2.3 Antioxidant Compounds Isolated from Endolichenic Fungi -- 2.4 Antibacterial Compounds Isolated from Endolichenic Fungi -- 2.5 Antiviral Compounds Isolated from Endolichenic Fungi -- 2.6 Anti-Inflammatory Compounds Isolated from Endolichenic Fungi -- 3 Classification of Bioactive Compounds According to Selected Taxa of Their Endolichenic Fungi -- 4 Summary Statement -- References |
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Chapter 5: Endolichenic Fungi, an Emerging Source of Bioactive Compounds: A Pharmaceutical Perspective -- 1 Introduction -- 2 Anticancer Compounds -- 3 Anti-Microbial Compounds -- 3.1 Antibacterial Compounds -- 3.2 Antifungal Compounds -- 4 Anti-Inflammatory Compounds -- 5 Anti-Alzheimer Compounds -- 6 Antioxidant Compounds -- 7 AChE Inhibitors -- 8 Phytotoxic Compounds -- 9 Antithrombotic Compounds -- 10 Conclusion -- References -- Part III: Marine Fungi as a Source of Medicinal Compounds |
| Summary |
This book presents the exploration and exploitation of various bioactive metabolites obtained from fungi isolated from diverse habitats for pharmaceutical applications. Various fungal sources have been brought under one umbrella ranging from endophytes, marine fungi, endolichenic fungi to fungi existing in the extremophilic conditions like desert and Antarctica and Artic environment. The book tries to cover maximally the range of the pharmaceutical applications wherein these bioactive agents from fungi have been exploited or are in the clinical pipelines and primarily include antibacterial, antifungal, antibiofilm, anticancer, antioxidant, autoimmunological, anti-inflammatory, and anti-thrombotic diseases. The book further emphasizes on the novel strategies to screen or enhance secondary metabolite production. Some other topics includes peptides, nonpeptides drugs, pigments, and enhancement of production of Echinocandin and Kojic acid. The role of bioinformatics in drug discovery and biotransformations have also been discussed. This book is going to be a comprehensive treatise and a valuable source for mycologists, biotechnologists, microbiologists, biotechnologists, and undertaking research in pharmaceutical sector as well as academia in setting up their research aspirations for using fungi in the process of drug discovery and development |
| Notes |
Description based upon print version of record |
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Chapter 6: Antibiofilm Metabolites from Sponge-Derived Aspergillus, Penicillium, and Fusarium for the Antibiotic Pipeline |
| Subject |
Fungal metabolites.
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Fungi -- Therapeutic use.
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| Genre/Form |
Electronic books
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| Form |
Electronic book
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| Author |
Takahashi, Jacqueline Aparecida
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Saxena, Sanjai
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| ISBN |
9789819956968 |
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981995696X |
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