| Description |
1 online resource : illustrations (some color) |
| Series |
Tumors of the Central Nervous System ; 8 |
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Tumors of the central nervous system ; 8.
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| Contents |
Part 1. Astrocytoma. Astrocytoma Cell Line: Role of Brain Natriuretic Peptide / Tomohiro Osanai, Chisato Katoh and Ken Okumura -- Malignant Brain Astrocytomas: Extent of Resection Affects Survival / Kaisorn L. Chaichana and Matthew J. McGirt |
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Part 2. Medulloblastoma. Medulloblastoma: Classification (A Review) / Valentina Caracciolo and Antonio Giordano -- Medulloblastomas: Clinically Important MicroRNA Genes / Deepak Kamnasaran -- Medulloblastoma: Role of OTX2 Transcription Factors / Austin Mattox, Jing Li, Chunhui Di and D. Cory Adamson -- Molecular Mechanisms of Chemoresistance in Medulloblastoma / Violaine Sée, Barry Pizer and Daniel Meley -- Extraneural Metastasis in Medulloblastoma / Arnold C. Paulino -- Medulloblastoma: Therapy with Bortezomib/Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand / Ronald Koschny, Peter Ahnert and Heidrun Holland -- Standard-Risk Medulloblastoma: Hyperfractionated Radiotherapy / Christian Carrie and Marie-Pierre Sunyach |
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Part 3. Retinoblastoma. Retinoma and Retinoblastoma: Genomic Hybridisation / Mariangela Amenduni, Gabriella Livide, Francesca Ariani and Alessandra Renieri -- Cell Cycle Control by Ataxia Telangiectasia Mutated Protein Through Regulating Retinoblastoma Protein Phosphorylation / Javier G. Pizarro, Antoni Camins, Felix Junyent, Ester Verdaguer and Carme Auladell, et al. -- Role of Survivin in Retinoblastoma: Diagnosis and Prognosis / Hanan Shehata, Azza Abou Ghalia and Eman Elsayed -- Retinoblastoma Epigenetics / Domenico Mastrangelo, Cosimo Loré and Giovanni Grasso -- Retinoblastoma: Disease, Diagnosis, Therapy and Management / Madhavan Jagadeesan, Sudhir Sudrik and Vikas Khetan -- Long-Term Survivors of Retinoblastoma: Risk of Increased Second Malignancy / Annette C. Moll, Tamara Marees, Machteld I. Bosscha and Flora E. van Leeuwen -- New Cancers Among Long-Term Survivors of Retinoblastoma / Alessandro Franchi |
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Part 4. Chordoma. Chordoma: Role of CAM5.2 / Takahiko Naka -- Chordomas and Chondrosarcomas: Treatment with Particle Radiotherapy / Daniela Schulz-Ertner -- Skull Base Chordomas: Endonasal Endoscopic Transclival Approach / Daniel M.S. Raper, Ricardo J. Komotar, Justin F. Fraser, Vijay K. Anand and Nicholas Moore, et al |
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Part 5. Craniopharyngioma. Craniopharyngioma: Comparison Between Supra-orbital Versus Endonasal Keyhole Approaches / Nancy McLaughlin, Amin B. Kassam, Daniel M. Prevedello, Domenico Solari and Kiarash Shahlaie, et al. -- The Expanded Endoscopic Endonasal Approach for Primary and Recurrent Craniopharyngiomas / Domenico Solari, Daniel M. Prevedello, Daniel F. Kelly, Nancy McLaughlin and Leo F.S. Ditzel Filho, et al. -- Craniopharyngioma: The Role of Radiation / John Varlotto, Cheng Saw, Richard Croley and Martin Pavelic -- Cystic Craniopharyngiomas: Intratumoral Bleomycin Therapy / Paul Steinbok and Juliette Hukin |
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Part 6. Oligodendroglioma. Anaplastic Oligodendroglioma Metastasized to Extraneural Sites / Metka Volavšek and Mara Popović -- Recurrent Oligodendroglioma: Treatment with Bevacizumab / Marc C. Chamberlain |
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Part 7. Ependymoma. Ependymoma: An Overview / Cynthia J. Campen and Paul Graham Fisher -- Ependymomas: Prognosis Based on Genetic Aberrations / Camelia-Maria Monoranu, Bei Huang and Gentner Doreen -- Aberrant DNA Methylation in Ependymomas / Min Wang and Hehuang Xie -- Progressively Metastasizing Ependymoma: Genomic Aberrations / Hendrik Witt, Andrey Korshunov, Marc Remke, Stefan M. Pfister and Olaf Witt, et al. -- Extradural Ependymoma: Diagnosis Using Magnetic Resonance Imaging / Nicola Montano, Quintino Giorgio D'Alessandris and Roberto Pallini -- Primary Malignant Ependymoma of the Abdominal Cavity: Diagnosis / Carolin Mogler and Wolf Mueller -- Atypical Histologic Features and Patterns of Malignant Evolution in Tanycytic Ependymoma / Istvan Vajtai and Ekkehard Hewer -- Intracranial Ependymoma: Role for Chemotherapy / Marc C. Chamberlain |
| Summary |
Annotation With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well as describing the delineation of prognosis based on the genetic aberrations of the latter patients. The material offers key insights into the molecular pathways involved in tumor biology, such as the role of E-cadherin gene instability, carbonic anhydrase II, urokinase plasminogen activator, and Wnt signaling in meningioma. Contributors explain the genetic and clinical features associated with recurring meningioma, including the role played by erythropoietin receptor, and examine the way in which OTX2 transcription factor functions as an oncogene in medulloblastoma. With much more besides, including discussion of the molecular mechanisms that result in resistance to chemotherapy in medulloblastoma, this volume and its companions have a positive role to play in inspiring a new generation of researchers to design new drugs that are better targetedand thus more effective |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
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Print version record |
| Subject |
Brain -- Tumors.
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Brain Neoplasms
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Neuroectodermal Tumors
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HEALTH & FITNESS -- Diseases -- Cancer.
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MEDICAL -- Oncology.
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Médecine.
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Brain -- Tumors
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| Form |
Electronic book
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| Author |
Hayat, M. A., 1940-
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| ISBN |
9789400742130 |
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9400742134 |
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