Limit search to available items
9 results found. Sorted by relevance | date | title .
Book Cover
Author Chu, Cong-Qiu

Title Targeting the IL-17 pathway in inflammatory disorders / Cong-Qiu Chu
Published Cham, Switzerland : Adis, [2017]


Description 1 online resource
Contents Introduction -- Overview of IL-17 family.-Il-17 in host defense -- Th17 cells: differentiation and regulation -- The role of the IL-17/Th17 pathway in the pathogenesis of autoimmune inflammatory diseases -- Therapeutic applications: strategies and molecules targeting the IL-17/Th17 pathway -- Concluding remarks
Summary This book provides an overview of the discovery and structure of IL-17, including its pathogenesis and role in chronic inflammation and autoimmunity. To capture the latest developments and product approvals the book also discusses the therapeutic advances and looks at emerging therapies targeting the IL-17 pathway. IL-17 is a pro-inflammatory cytokine that has a key role in inflammation, autoimmunity, and host defense in a number of inflammatory disorders such as rheumatoid arthritis, psoriatic arthritis and psoriasis, ankylosing spondylitis, multiple sclerosis, and inflammatory bowel disease. The discovery of the IL-17-Th17 pathway has seen exciting development in the field of immunology and inflammation research, which has led to a number of recent regulatory approvals
Bibliography Includes bibliographical references
Notes Print version record
Subject Interleukins.
Interleukin-17 -- immunology
Th17 Cells -- chemistry
Anti-Inflammatory Agents -- therapeutic use
Drug Delivery Systems
Inflammation -- drug therapy
Interleukin-17 -- antagonists & inhibitors
SCIENCE -- Life Sciences -- Anatomy & Physiology.
Form Electronic book
ISBN 9783319280400