| Description |
1 online resource (xi, 341 pages) : illustrations (some color) |
| Series |
Methods in molecular medicine, 1940-6029 ; 1387 |
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Springer protocols |
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Methods in molecular biology (Clifton, N.J.) ; v. 1387. 1064-3745
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Springer protocols (Series) 1949-2448
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| Contents |
Introduction to poliovirus : pathogenesis, vaccination, and the endgame for global eradication / Philip D. Minor -- Poliovirus laboratory based surveillance : an overview / Syed Sohail Zahoor Zaidi [and others] -- Isolation and characterization of enteroviruses from clinical samples / Soile Blomqvist and Merja Roivainen -- Isolation and characterization of poliovirus in cell culture systems / Bruce R. Thorley and Jason A. Roberts -- Molecular characterization of polio from environmental samples : ISSP, the Israeli sewage surveillance protocol / Lester M. Shulman [and others] -- Quality assurance in the polio laboratory. Cell sensitivity and cell authentication assays / Glynis Dunn -- Transgenic mouse model of poliomyelitis / Satoshi Koike and Noriyo Nagata -- Standardized methods for detection of poliovirus antibodies / William C. Weldon [and others] -- Molecular properties of poliovirus isolates : nucleotide sequence analysis, typing by PCR and real-time RT-PCR / Cara C. Burns [and others] -- Isolation and characterization of vaccine-derived polioviruses, relevance for the global polio eradication initiative / Wenbo Xu and Yong Zhang -- Phylogenetic analysis of poliovirus sequences / Jaume Jorba -- Generation of infectious poliovirus with altered genetic information from cloned cDNA / Erika Bujaki -- Rapid method for engineering recombinant polioviruses or other enteroviruses / Maël Bessaud [and others] -- Methods to monitor molecular consistency of oral polio vaccine / Konstantin M. Chumakov -- Methods for the quality control of inactivated poliovirus vaccines / Thomas Wilton -- Measuring poliovirus antigenicity by surface plasmon resonance. Application for potency indicating assays / Janny Westdijk [and others] -- Identification and analysis of antiviral compounds against poliovirus / Pieter Leyssen [and others] |
| Summary |
This volume introduces the reader to the field of systems medicine by defining its terminology, and describing how established computational methods from bioinformatics and systems biology can be taken forward to establish integrative systems medicine approaches. Systems Medicine provides an outlook on the role that systems medicine may or should play in various medical fields. Describing different facets of the systems medicine approach in action, including examples related to human metabolism, chronic obstructive pulmonary disease, the RNAs in biomedicine and regenerative stem cell medicine. Chapters also introduce tools, resources and methodologies from bioinformatics and systems biology, and shows how to apply these in a systems medicine project. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, and discuss experimental and computational approaches, methods, and tools that should be considered for a successful systems medicine project. Systems Medicine aims to motivate and provide guidance for collaborations across disciplines to tackle today's challenges related to human health and well-being |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Poliovirus.
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Genetics -- Technique.
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Poliovirus
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Genetic Techniques
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Immunologic Techniques
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Medical microbiology & virology.
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Infectious & contagious diseases.
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Medical -- Microbiology.
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Medical -- Infectious Diseases.
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Genetics -- Technique
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Poliovirus
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| Genre/Form |
Laboratory manuals
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Laboratory manuals.
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Manuels de laboratoire.
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| Form |
Electronic book
|
| Author |
Martín, Javier, Dr.
|
| ISBN |
9781493932924 |
|
1493932926 |
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1493932918 |
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9781493932917 |
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