| Description |
1 online resource (xxv, 301 pages) : illustrations (chiefly color) |
| Contents |
Intro -- Foreword -- Preface -- Disclaimer -- Contents -- Editors -- Contributors -- Abbreviations -- 1: The International System for Reporting Serous Fluid Cytopathology: Introduction and Overview of Diagnostic Terminology and Reporting -- Introduction -- Format of the Report -- Rate and Risk of Malignancy -- References -- 2: Non-diagnostic (ND) and Adequacy -- Background -- Definition -- Explanatory Notes -- Clinical Management -- Sample Reports -- References -- 3: Negative for Malignancy (NFM) -- Background -- Definition -- Criteria for Negative for Malignancy -- Explanatory Notes |
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Approach to Serous Effusion (Fig. 3.1) -- Expected Cellular Findings -- Without Regard to Volume or Distribution -- With Increased Volume and/or Distribution of Predominately One Cell Type -- Predominantly Mesothelial Cells -- Predominantly Histiocytes -- Predominantly Lymphocytes -- Predominantly or Increased Eosinophils -- Predominantly Neutrophils -- Unexpected Cellular and Noncellular Findings -- Unexpected Cell Population (Second Cell Population) -- Unexpected Benign Cellular and Noncellular Findings -- Psammoma Bodies -- Collagen Balls -- Detached Ciliary Tufts |
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Asbestos (Ferruginous) Bodies -- Curschmann's Spirals -- Lupus Erythematosus (LE) Cells -- Necrotic Material -- Fistula -- Infectious Organisms -- Rate and Risk of Malignancy -- Sample Reports -- References -- 4: Atypia of Undetermined Significance -- Background -- Definition -- Criteria -- Explanatory Notes -- Sample Reports -- Rate and Risk of Malignancy -- References -- 5: Suspicious for Malignancy (SFM) -- Definition -- Cytologic Criteria -- Explanatory Notes -- Rate and Risk of Malignancy/Clinical Management -- Sample Reports -- References -- 6: Malignant-Primary (MAL-P) (Mesothelioma) |
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Introduction -- Background -- Cytological Approach to Fluids -- Malignant Mesothelioma -- Definition -- Gross Findings of Serous Effusion -- Cytologic Criteria -- Definitive Criteria of Malignancy [10-18] (Fig. 6.10) -- Supportive Criteria of Malignancy (Figs. 6.11, 6.12, 6.13 and 6.14) -- Explanatory Notes -- Role of Immunochemistry (IC) in the Work-Up of Mesothelioma -- Immunochemistry on Cell Block Versus Smears -- Determining Benign Versus Malignant Mesothelial Cells -- Determining Malignant Mesothelioma Versus Carcinoma -- Determining Mesothelioma Versus Non-epithelial Malignancies |
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Prognostic and Predictive Markers for Malignant Mesothelioma -- Role of FISH -- Role of Soluble Biomarkers -- Risk of Malignancy/Clinical Management -- Sample Reports -- References -- 7: Malignant-Secondary (MAL-S) -- Background -- Definition -- Diagnostic Approach -- Malignant Effusions of Epithelial Origin -- Adenocarcinoma -- Cytological Criteria -- Explanatory Notes -- Squamous Cell Carcinoma -- Cytological Criteria -- Explanatory Notes -- Other Carcinomas -- Cytological Criteria -- Malignant Effusions of Neuroendocrine Origin -- Small Cell Neuroendocrine Carcinoma -- Cytological Criteria |
| Summary |
This book is the culmination of an international effort to bring consistency and diagnostic efficiency to effusion cytology for the sake of patient care. The authors recognize special challenges in serous fluid cytopathology, such as reporting the presence of Mullerian epithelium in peritoneal fluids. What is an appropriate serous fluid volume to ensure adequacy? How should mesothelial proliferations be reported and is it appropriate to make an interpretation of malignant mesothelioma? How specific should a report be regarding the origin and subtyping of tumors found in serous fluids? What are the appropriate quality monitors for this specimen type? Special chapters on considerations for peritoneal washings, cytopreparatory techniques, mesothelioma and quality management are included to address these issues. The text contains literature reviews that elucidate existing evidence in support of current practices and recommendations. Expert opinions on where evidence was lacking, the most common practices were adopted by consensus, and where there was no commonality, are employed. Written by experts in the field, The International System for Serous Fluid Cytopathology serves as a collaborative effort between the International Academy of Cytology and the American Society for Cytopathology and calls upon participation of the international cytopathology and oncology communities to contribute to the development of a truly international system for reporting serous fluid cytology |
| Notes |
Online resource; title from digital title page (viewed on January 28, 2021) |
| Subject |
Serous fluids -- Cytopathology
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Pathology
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| Form |
Electronic book
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| Author |
Chandra, Ashish (Histopathologist), editor.
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Crothers, Barbara, editor
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Kurtycz, Daniel, editor
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Schmitt, Fernando, editor.
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| ISBN |
3030539083 |
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9783030539085 |
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